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Diagnostics and correction of batch effects in large-scale proteomic studies: a tutorial.
Čuklina J, Lee CH, Williams EG, Sajic T, Collins BC, Rodríguez Martínez M, Sharma VS, Wendt F, Goetze S, Keele GR, Wollscheid B, Aebersold R, Pedrioli PGA. Čuklina J, et al. Among authors: keele gr. Mol Syst Biol. 2021 Aug;17(8):e10240. doi: 10.15252/msb.202110240. Mol Syst Biol. 2021. PMID: 34432947 Free PMC article. Review.
Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression.
Yu Q, Liu X, Keller MP, Navarrete-Perea J, Zhang T, Fu S, Vaites LP, Shuken SR, Schmid E, Keele GR, Li J, Huttlin EL, Rashan EH, Simcox J, Churchill GA, Schweppe DK, Attie AD, Paulo JA, Gygi SP. Yu Q, et al. Among authors: keele gr. Nat Commun. 2023 Feb 2;14(1):555. doi: 10.1038/s41467-023-36269-7. Nat Commun. 2023. PMID: 36732331 Free PMC article.
Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency.
Skelly DA, Czechanski A, Byers C, Aydin S, Spruce C, Olivier C, Choi K, Gatti DM, Raghupathy N, Keele GR, Stanton A, Vincent M, Dion S, Greenstein I, Pankratz M, Porter DK, Martin W, O'Connor C, Qin W, Harrill AH, Choi T, Churchill GA, Munger SC, Baker CL, Reinholdt LG. Skelly DA, et al. Among authors: keele gr. Cell Stem Cell. 2020 Sep 3;27(3):459-469.e8. doi: 10.1016/j.stem.2020.07.005. Epub 2020 Aug 13. Cell Stem Cell. 2020. PMID: 32795400 Free PMC article.
A large-scale genome-lipid association map guides lipid identification.
Linke V, Overmyer KA, Miller IJ, Brademan DR, Hutchins PD, Trujillo EA, Reddy TR, Russell JD, Cushing EM, Schueler KL, Stapleton DS, Rabaglia ME, Keller MP, Gatti DM, Keele GR, Pham D, Broman KW, Churchill GA, Attie AD, Coon JJ. Linke V, et al. Among authors: keele gr. Nat Metab. 2020 Oct;2(10):1149-1162. doi: 10.1038/s42255-020-00278-3. Epub 2020 Sep 21. Nat Metab. 2020. PMID: 32958938 Free PMC article.
A Bayesian model selection approach to mediation analysis.
Crouse WL, Keele GR, Gastonguay MS, Churchill GA, Valdar W. Crouse WL, et al. Among authors: keele gr. PLoS Genet. 2022 May 9;18(5):e1010184. doi: 10.1371/journal.pgen.1010184. eCollection 2022 May. PLoS Genet. 2022. PMID: 35533209 Free PMC article.
Regulation of protein abundance in genetically diverse mouse populations.
Keele GR, Zhang T, Pham DT, Vincent M, Bell TA, Hock P, Shaw GD, Paulo JA, Munger SC, de Villena FP, Ferris MT, Gygi SP, Churchill GA. Keele GR, et al. Cell Genom. 2021 Oct 13;1(1):100003. doi: 10.1016/j.xgen.2021.100003. Epub 2021 Sep 3. Cell Genom. 2021. PMID: 36212994 Free PMC article.
37 results