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Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism.
Monteiro C, Miarka L, Perea-García M, Priego N, García-Gómez P, Álvaro-Espinosa L, de Pablos-Aragoneses A, Yebra N, Retana D, Baena P, Fustero-Torre C, Graña-Castro O, Troulé K, Caleiras E, Tezanos P, Muela P, Cintado E, Trejo JL, Sepúlveda JM, González-León P, Jiménez-Roldán L, Moreno LM, Esteban O, Pérez-Núñez Á, Hernández-Lain A, Mazarico Gallego J, Ferrer I, Suárez R, Garrido-Martín EM, Paz-Ares L, Dalmasso C, Cohen-Jonathan Moyal E, Siegfried A, Hegarty A, Keelan S, Varešlija D, Young LS, Mohme M, Goy Y, Wikman H, Fernández-Alén J, Blasco G, Alcázar L, Cabañuz C, Grivennikov SI, Ianus A, Shemesh N, Faria CC, Lee R, Lorigan P, Le Rhun E, Weller M, Soffietti R, Bertero L, Ricardi U, Bosch-Barrera J, Sais E, Teixidor E, Hernández-Martínez A, Calvo A, Aristu J, Martin SM, Gonzalez A, Adler O, Erez N; RENACER; Valiente M. Monteiro C, et al. Among authors: keelan s. Nat Med. 2022 Apr;28(4):752-765. doi: 10.1038/s41591-022-01749-8. Epub 2022 Apr 11. Nat Med. 2022. PMID: 35411077 Free PMC article.
ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis.
Charmsaz S, Doherty B, Cocchiglia S, Varešlija D, Marino A, Cosgrove N, Marques R, Priedigkeit N, Purcell S, Bane F, Bolger J, Byrne C, O'Halloran PJ, Brett F, Sheehan K, Brennan K, Hopkins AM, Keelan S, Jagust P, Madden S, Martinelli C, Battaglini M, Oesterreich S, Lee AV, Ciofani G, Hill ADK, Young LS. Charmsaz S, et al. Among authors: keelan s. BMC Med. 2020 Nov 19;18(1):349. doi: 10.1186/s12916-020-01806-4. BMC Med. 2020. PMID: 33208158 Free PMC article.
Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities.
Cosgrove N, Varešlija D, Keelan S, Elangovan A, Atkinson JM, Cocchiglia S, Bane FT, Singh V, Furney S, Hu C, Carter JM, Hart SN, Yadav S, Goetz MP, Hill ADK, Oesterreich S, Lee AV, Couch FJ, Young LS. Cosgrove N, et al. Among authors: keelan s. Nat Commun. 2022 Jan 26;13(1):514. doi: 10.1038/s41467-022-27987-5. Nat Commun. 2022. PMID: 35082299 Free PMC article.
Dynamic epi-transcriptomic landscape mapping with disease progression in estrogen receptor-positive breast cancer.
Keelan S, Ola M, Charmsaz S, Cocchiglia S, Ottaviani D, Hickey S, Purcell S, Bane F, Hegarty A, Doherty B, Sheehan K, Hudson L, Cosgrove N, Roux B, Laine M, Greene G, Varešlija D, Hill AK, Young L. Keelan S, et al. Cancer Commun (Lond). 2023 May;43(5):615-619. doi: 10.1002/cac2.12407. Epub 2023 Jan 20. Cancer Commun (Lond). 2023. PMID: 36670046 Free PMC article. No abstract available.
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