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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 1
2006 1
2007 1
2008 2
2009 1
2010 3
2011 4
2012 2
2013 4
2014 3
2015 2
2016 2
2017 8
2018 3
2019 7
2020 4
2021 6
2022 5
2023 4
2024 1

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61 results

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Page 1
GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants.
Aoki M, Aoki-Ogata H, Bulut H, Hayashi H, Takamune N, Kishimoto N, Tanaka H, Higashi-Kuwata N, Hattori SI, Das D, Venkateswara Rao K, Iwama K, Davis DA, Hasegawa K, Murayama K, Yarchoan R, Ghosh AK, Pau AK, Machida S, Misumi S, Mitsuya H. Aoki M, et al. Among authors: hasegawa k. Sci Adv. 2023 Jul 14;9(28):eadg2955. doi: 10.1126/sciadv.adg2955. Epub 2023 Jul 12. Sci Adv. 2023. PMID: 37436982 Free PMC article.
Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.
Higashi-Kuwata N, Tsuji K, Hayashi H, Bulut H, Kiso M, Imai M, Ogata-Aoki H, Ishii T, Kobayakawa T, Nakano K, Takamune N, Kishimoto N, Hattori SI, Das D, Uemura Y, Shimizu Y, Aoki M, Hasegawa K, Suzuki S, Nishiyama A, Saruwatari J, Shimizu Y, Sukenaga Y, Takamatsu Y, Tsuchiya K, Maeda K, Yoshimura K, Iida S, Ozono S, Suzuki T, Okamura T, Misumi S, Kawaoka Y, Tamamura H, Mitsuya H. Higashi-Kuwata N, et al. Among authors: hasegawa k. Nat Commun. 2023 Feb 25;14(1):1076. doi: 10.1038/s41467-023-36729-0. Nat Commun. 2023. PMID: 36841831 Free PMC article.
Structure and biological evaluation of Caenorhabditis elegans CISD-1/mitoNEET, a KLP-17 tail domain homologue, supports attenuation of paraquat-induced oxidative stress through a p38 MAPK-mediated antioxidant defense response.
Boos JR, Jandrain HN, Hagiuda E, Taguchi AT, Hasegawa K, Fedun BL, Taylor SJ, Elad SM, Faber SE, Kumasaka T, Iwasaki T, Geldenhuys WJ. Boos JR, et al. Among authors: hasegawa k. Adv Redox Res. 2022 Dec;6:100048. doi: 10.1016/j.arres.2022.100048. Epub 2022 Sep 23. Adv Redox Res. 2022. PMID: 36533211 Free PMC article.
Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors.
Makino Y, Oe C, Iwama K, Suzuki S, Nishiyama A, Hasegawa K, Okuda H, Hirata K, Ueno M, Kawaji K, Sasano M, Usui E, Hosaka T, Yabuki Y, Shirouzu M, Katsumi M, Murayama K, Hayashi H, Kodama EN. Makino Y, et al. Among authors: hasegawa k. Commun Biol. 2022 Jun 23;5(1):619. doi: 10.1038/s42003-022-03555-x. Commun Biol. 2022. PMID: 35739195 Free PMC article.
In situ crystal data-collection and ligand-screening system at SPring-8.
Okumura H, Sakai N, Murakami H, Mizuno N, Nakamura Y, Ueno G, Masunaga T, Kawamura T, Baba S, Hasegawa K, Yamamoto M, Kumasaka T. Okumura H, et al. Among authors: hasegawa k. Acta Crystallogr F Struct Biol Commun. 2022 Jun 1;78(Pt 6):241-251. doi: 10.1107/S2053230X22005283. Epub 2022 May 27. Acta Crystallogr F Struct Biol Commun. 2022. PMID: 35647681 Free PMC article.
Radiation-induced defects in protein crystals observed by X-ray topography.
Suzuki R, Baba S, Mizuno N, Hasegawa K, Koizumi H, Kojima K, Kumasaka T, Tachibana M. Suzuki R, et al. Among authors: hasegawa k. Acta Crystallogr D Struct Biol. 2022 Feb 1;78(Pt 2):196-203. doi: 10.1107/S205979832101281X. Epub 2022 Jan 21. Acta Crystallogr D Struct Biol. 2022. PMID: 35102885
Fluorine Modifications Contribute to Potent Antiviral Activity against Highly Drug-Resistant HIV-1 and Favorable Blood-Brain Barrier Penetration Property of Novel Central Nervous System-Targeting HIV-1 Protease Inhibitors In Vitro.
Amano M, Yedidi RS, Salcedo-Gómez PM, Hayashi H, Hasegawa K, Martyr CD, Ghosh AK, Mitsuya H. Amano M, et al. Among authors: hasegawa k. Antimicrob Agents Chemother. 2022 Feb 15;66(2):e0171521. doi: 10.1128/AAC.01715-21. Epub 2022 Jan 3. Antimicrob Agents Chemother. 2022. PMID: 34978889 Free PMC article.
61 results