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Cell death.
Newton K, Strasser A, Kayagaki N, Dixit VM. Newton K, et al. Among authors: kayagaki n. Cell. 2024 Jan 18;187(2):235-256. doi: 10.1016/j.cell.2023.11.044. Cell. 2024. PMID: 38242081 Free article. Review.
Control of Cell Death in Health and Disease.
Kayagaki N, Webster JD, Newton K. Kayagaki N, et al. Annu Rev Pathol. 2024 Jan 24;19:157-180. doi: 10.1146/annurev-pathmechdis-051022-014433. Epub 2023 Oct 3. Annu Rev Pathol. 2024. PMID: 37788577 Free article. Review.
Epigenetic and transcriptional control of gasdermins.
Cadena C, Kornfeld OS, Lee BL, Kayagaki N. Cadena C, et al. Among authors: kayagaki n. Semin Immunol. 2023 Nov;70:101841. doi: 10.1016/j.smim.2023.101841. Epub 2023 Sep 11. Semin Immunol. 2023. PMID: 37703611 Review.
Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury.
Kayagaki N, Stowe IB, Alegre K, Deshpande I, Wu S, Lin Z, Kornfeld OS, Lee BL, Zhang J, Liu J, Suto E, Lee WP, Schneider K, Lin W, Seshasayee D, Bhangale T, Chalouni C, Johnson MC, Joshi P, Mossemann J, Zhao S, Ali D, Goldenberg NM, Sayed BA, Steinberg BE, Newton K, Webster JD, Kelly RL, Dixit VM. Kayagaki N, et al. Nature. 2023 Jun;618(7967):1072-1077. doi: 10.1038/s41586-023-06191-5. Epub 2023 May 17. Nature. 2023. PMID: 37196676 Free PMC article.
Dying cells fan the flames of inflammation.
Newton K, Dixit VM, Kayagaki N. Newton K, et al. Among authors: kayagaki n. Science. 2021 Nov 26;374(6571):1076-1080. doi: 10.1126/science.abi5934. Epub 2021 Nov 25. Science. 2021. PMID: 34822265 Review.
Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection.
Luchetti G, Roncaioli JL, Chavez RA, Schubert AF, Kofoed EM, Reja R, Cheung TK, Liang Y, Webster JD, Lehoux I, Skippington E, Reeder J, Haley B, Tan MW, Rose CM, Newton K, Kayagaki N, Vance RE, Dixit VM. Luchetti G, et al. Among authors: kayagaki n. Cell Host Microbe. 2021 Oct 13;29(10):1521-1530.e10. doi: 10.1016/j.chom.2021.08.010. Epub 2021 Sep 6. Cell Host Microbe. 2021. PMID: 34492225 Free PMC article.
Selective activation of PFKL suppresses the phagocytic oxidative burst.
Amara N, Cooper MP, Voronkova MA, Webb BA, Lynch EM, Kollman JM, Ma T, Yu K, Lai Z, Sangaraju D, Kayagaki N, Newton K, Bogyo M, Staben ST, Dixit VM. Amara N, et al. Among authors: kayagaki n. Cell. 2021 Aug 19;184(17):4480-4494.e15. doi: 10.1016/j.cell.2021.07.004. Epub 2021 Jul 27. Cell. 2021. PMID: 34320407 Free PMC article.
NINJ1 mediates plasma membrane rupture during lytic cell death.
Kayagaki N, Kornfeld OS, Lee BL, Stowe IB, O'Rourke K, Li Q, Sandoval W, Yan D, Kang J, Xu M, Zhang J, Lee WP, McKenzie BS, Ulas G, Payandeh J, Roose-Girma M, Modrusan Z, Reja R, Sagolla M, Webster JD, Cho V, Andrews TD, Morris LX, Miosge LA, Goodnow CC, Bertram EM, Dixit VM. Kayagaki N, et al. Nature. 2021 Mar;591(7848):131-136. doi: 10.1038/s41586-021-03218-7. Epub 2021 Jan 20. Nature. 2021. PMID: 33472215
106 results