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WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.
Mitchell K, Sprowls SA, Arora S, Shakya S, Silver DJ, Goins CM, Wallace L, Roversi G, Schafer RE, Kay K, Miller TE, Lauko A, Bassett J, Kashyap A, D'Amato Kass J, Mulkearns-Hubert EE, Johnson S, Alvarado J, Rich JN, Holland EC, Paddison PJ, Patel AP, Stauffer SR, Hubert CG, Lathia JD. Mitchell K, et al. Among authors: kay k. Genes Dev. 2023 Feb 1;37(3-4):86-102. doi: 10.1101/gad.349803.122. Epub 2023 Feb 2. Genes Dev. 2023. PMID: 36732025 Free PMC article.
Sex Differences in Glioblastoma Immunotherapy Response.
Lee J, Kay K, Troike K, Ahluwalia MS, Lathia JD. Lee J, et al. Among authors: kay k. Neuromolecular Med. 2022 Mar;24(1):50-55. doi: 10.1007/s12017-021-08659-x. Epub 2021 Apr 17. Neuromolecular Med. 2022. PMID: 33864598 Review.
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity.
Watson DC, Bayik D, Storevik S, Moreino SS, Sprowls SA, Han J, Augustsson MT, Lauko A, Sravya P, Røsland GV, Troike K, Tronstad KJ, Wang S, Sarnow K, Kay K, Lunavat TR, Silver DJ, Dayal S, Joseph JV, Mulkearns-Hubert E, Ystaas LAR, Deshpande G, Guyon J, Zhou Y, Magaut CR, Seder J, Neises L, Williford SE, Meiser J, Scott AJ, Sajjakulnukit P, Mears JA, Bjerkvig R, Chakraborty A, Daubon T, Cheng F, Lyssiotis CA, Wahl DR, Hjelmeland AB, Hossain JA, Miletic H, Lathia JD. Watson DC, et al. Among authors: kay k. Nat Cancer. 2023 May;4(5):648-664. doi: 10.1038/s43018-023-00556-5. Epub 2023 May 11. Nat Cancer. 2023. PMID: 37169842 Free PMC article.
Correction: Distinct Cell Adhesion Signature Defines Glioblastoma Myeloid-Derived Suppressor Cell Subsets.
Bayik D, Bartels CF, Lovrenert K, Watson DC, Zhang D, Kay K, Lee J, Lauko A, Johnson S, Lo A, Silver DJ, McGraw M, Grabowski M, Mohammadi AM, Veglia F, Fan Y, Vogelbaum MA, Scacheri P, Lathia JD. Bayik D, et al. Among authors: kay k. Cancer Res. 2023 May 15;83(10):1757. doi: 10.1158/0008-5472.CAN-23-0773. Cancer Res. 2023. PMID: 37183658 Free PMC article. No abstract available.
Metaorganismal choline metabolism shapes olfactory perception.
Massey WJ, Kay KE, Jaramillo TC, Horak AJ 3rd, Cao S, Osborn LJ, Banerjee R, Mrdjen M, Hamoudi MK, Silver DJ, Burrows AC, Brown AL, Reizes O, Lathia JD, Wang Z, Hazen SL, Brown JM. Massey WJ, et al. Among authors: kay ke. J Biol Chem. 2023 Nov;299(11):105299. doi: 10.1016/j.jbc.2023.105299. Epub 2023 Sep 28. J Biol Chem. 2023. PMID: 37777156 Free PMC article.
Homeostatic iron regulatory protein drives glioblastoma growth via tumor cell-intrinsic and sex-specific responses.
Troike KM, Wang SZ, Silver DJ, Lee J, Mulkearns-Hubert EE, Hajdari N, Ghosh PK, Kay KE, Beilis JL, Mitchell SE, Bishop CW, Hong ES, Artomov M, Hubert CG, Rajappa P, Connor JR, Fox PL, Kristensen BW, Lathia JD. Troike KM, et al. Among authors: kay ke. Neurooncol Adv. 2023 Nov 28;6(1):vdad154. doi: 10.1093/noajnl/vdad154. eCollection 2024 Jan-Dec. Neurooncol Adv. 2023. PMID: 38239626 Free PMC article.
miR-644a is a tumor cell-intrinsic mediator of sex bias in glioblastoma.
Hong ES, Wang SZ, Ponti AK, Hajdari N, Lee J, Mulkearns-Hubert EE, Volovetz J, Kay KE, Lathia JD, Dhawan A. Hong ES, et al. Among authors: kay ke. bioRxiv [Preprint]. 2024 Mar 12:2024.03.11.584443. doi: 10.1101/2024.03.11.584443. bioRxiv. 2024. PMID: 38559056 Free PMC article. Preprint.
Androgen loss weakens anti-tumor immunity and accelerates brain tumor growth.
Lee J, Chung YM, Curtin L, Silver DJ, Hao Y, Li C, Volovetz J, Hong ES, Jarmula J, Wang SZ, Kay KE, Berens M, Nicosia M, Swanson KR, Sharifi N, Lathia JD. Lee J, et al. Among authors: kay ke. Res Sq [Preprint]. 2024 Mar 29:rs.3.rs-4014556. doi: 10.21203/rs.3.rs-4014556/v1. Res Sq. 2024. PMID: 38585839 Free PMC article. Preprint.
354 results