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Structural insights into 3Fe-4S ferredoxins diversity in M. tuberculosis highlighted by a first redox complex with P450.
Gilep A, Varaksa T, Bukhdruker S, Kavaleuski A, Ryzhykau Y, Smolskaya S, Sushko T, Tsumoto K, Grabovec I, Kapranov I, Okhrimenko I, Marin E, Shevtsov M, Mishin A, Kovalev K, Kuklin A, Gordeliy V, Kaluzhskiy L, Gnedenko O, Yablokov E, Ivanov A, Borshchevskiy V, Strushkevich N. Gilep A, et al. Among authors: kavaleuski a. Front Mol Biosci. 2023 Jan 9;9:1100032. doi: 10.3389/fmolb.2022.1100032. eCollection 2022. Front Mol Biosci. 2023. PMID: 36699703 Free PMC article.
A new twist of rubredoxin function in M. tuberculosis.
Sushko T, Kavaleuski A, Grabovec I, Kavaleuskaya A, Vakhrameev D, Bukhdruker S, Marin E, Kuzikov A, Masamrekh R, Shumyantseva V, Tsumoto K, Borshchevskiy V, Gilep A, Strushkevich N. Sushko T, et al. Among authors: kavaleuski a. Bioorg Chem. 2021 Apr;109:104721. doi: 10.1016/j.bioorg.2021.104721. Epub 2021 Feb 11. Bioorg Chem. 2021. PMID: 33618255
Metabolic Fate of Human Immunoactive Sterols in Mycobacterium tuberculosis.
Varaksa T, Bukhdruker S, Grabovec I, Marin E, Kavaleuski A, Gusach A, Kovalev K, Maslov I, Luginina A, Zabelskii D, Astashkin R, Shevtsov M, Smolskaya S, Kavaleuskaya A, Shabunya P, Baranovsky A, Dolgopalets V, Charnou Y, Savachka A, Litvinovskaya R, Hurski A, Shevchenko E, Rogachev A, Mishin A, Gordeliy V, Gabrielian A, Hurt DE, Nikonenko B, Majorov K, Apt A, Rosenthal A, Gilep A, Borshchevskiy V, Strushkevich N. Varaksa T, et al. Among authors: kavaleuski a. J Mol Biol. 2021 Feb 19;433(4):166763. doi: 10.1016/j.jmb.2020.166763. Epub 2020 Dec 24. J Mol Biol. 2021. PMID: 33359098
Hydroxylation of Antitubercular Drug Candidate, SQ109, by Mycobacterial Cytochrome P450.
Bukhdruker S, Varaksa T, Grabovec I, Marin E, Shabunya P, Kadukova M, Grudinin S, Kavaleuski A, Gusach A, Gilep A, Borshchevskiy V, Strushkevich N. Bukhdruker S, et al. Among authors: kavaleuski a. Int J Mol Sci. 2020 Oct 16;21(20):7683. doi: 10.3390/ijms21207683. Int J Mol Sci. 2020. PMID: 33081390 Free PMC article.
Mechanism of the Affinity-Enhancing Effect of Isatin on Human Ferrochelatase and Adrenodoxin Reductase Complex Formation: Implication for Protein Interactome Regulation.
Ershov PV, Veselovsky AV, Mezentsev YV, Yablokov EO, Kaluzhskiy LA, Tumilovich AM, Kavaleuski AA, Gilep AA, Moskovkina TV, Medvedev AE, Ivanov AS. Ershov PV, et al. Among authors: kavaleuski aa. Int J Mol Sci. 2020 Oct 14;21(20):7605. doi: 10.3390/ijms21207605. Int J Mol Sci. 2020. PMID: 33066693 Free PMC article.