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Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts.
Rodríguez-Hernández D, Vijayan K, Zigweid R, Fenwick MK, Sankaran B, Roobsoong W, Sattabongkot J, Glennon EKK, Myler PJ, Sunnerhagen P, Staker BL, Kaushansky A, Grøtli M. Rodríguez-Hernández D, et al. Among authors: kaushansky a. Nat Commun. 2023 Sep 5;14(1):5408. doi: 10.1038/s41467-023-41119-7. Nat Commun. 2023. PMID: 37669940 Free PMC article.
Complete Plasmodium falciparum liver-stage development in liver-chimeric mice.
Vaughan AM, Mikolajczak SA, Wilson EM, Grompe M, Kaushansky A, Camargo N, Bial J, Ploss A, Kappe SH. Vaughan AM, et al. Among authors: kaushansky a. J Clin Invest. 2012 Oct;122(10):3618-28. doi: 10.1172/JCI62684. Epub 2012 Sep 10. J Clin Invest. 2012. PMID: 22996664 Free PMC article.
Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites.
Douglass AN, Kain HS, Abdullahi M, Arang N, Austin LS, Mikolajczak SA, Billman ZP, Hume JCC, Murphy SC, Kappe SHI, Kaushansky A. Douglass AN, et al. Among authors: kaushansky a. Mol Ther. 2015 May;23(5):857-865. doi: 10.1038/mt.2015.18. Epub 2015 Feb 4. Mol Ther. 2015. PMID: 25648263 Free PMC article.
Plasmodium vivax liver stage development and hypnozoite persistence in human liver-chimeric mice.
Mikolajczak SA, Vaughan AM, Kangwanrangsan N, Roobsoong W, Fishbaugher M, Yimamnuaychok N, Rezakhani N, Lakshmanan V, Singh N, Kaushansky A, Camargo N, Baldwin M, Lindner SE, Adams JH, Sattabongkot J, Kappe SH. Mikolajczak SA, et al. Among authors: kaushansky a. Cell Host Microbe. 2015 Apr 8;17(4):526-35. doi: 10.1016/j.chom.2015.02.011. Epub 2015 Mar 19. Cell Host Microbe. 2015. PMID: 25800544 Free PMC article.
Opportunities for Host-targeted Therapies for Malaria.
Glennon EKK, Dankwa S, Smith JD, Kaushansky A. Glennon EKK, et al. Among authors: kaushansky a. Trends Parasitol. 2018 Oct;34(10):843-860. doi: 10.1016/j.pt.2018.07.011. Epub 2018 Aug 16. Trends Parasitol. 2018. PMID: 30122551 Free PMC article. Review.
Liver stage malaria infection is controlled by host regulators of lipid peroxidation.
Kain HS, Glennon EKK, Vijayan K, Arang N, Douglass AN, Fortin CL, Zuck M, Lewis AJ, Whiteside SL, Dudgeon DR, Johnson JS, Aderem A, Stevens KR, Kaushansky A. Kain HS, et al. Among authors: kaushansky a. Cell Death Differ. 2020 Jan;27(1):44-54. doi: 10.1038/s41418-019-0338-1. Epub 2019 May 7. Cell Death Differ. 2020. PMID: 31065106 Free PMC article.
Exciting Contributions to the Cryptosporidium Renaissance.
Vijayan K, Kaushansky A. Vijayan K, et al. Among authors: kaushansky a. Cell Host Microbe. 2019 Jul 10;26(1):5-7. doi: 10.1016/j.chom.2019.06.008. Cell Host Microbe. 2019. PMID: 31295425 Free article.
84 results