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Anti-Tumor Effects of Peptide Therapeutic and Peptide Vaccine Antibody Co-targeting HER-1 and HER-2 in Esophageal Cancer (EC) and HER-1 and IGF-1R in Triple-Negative Breast Cancer (TNBC).
Overholser J, Ambegaokar KH, Eze SM, Sanabria-Figueroa E, Nahta R, Bekaii-Saab T, Kaumaya PT. Overholser J, et al. Among authors: kaumaya pt. Vaccines (Basel). 2015 Jul 6;3(3):519-43. doi: 10.3390/vaccines3030519. Vaccines (Basel). 2015. PMID: 26350593 Free PMC article.
Phase I active immunotherapy with combination of two chimeric, human epidermal growth factor receptor 2, B-cell epitopes fused to a promiscuous T-cell epitope in patients with metastatic and/or recurrent solid tumors.
Kaumaya PT, Foy KC, Garrett J, Rawale SV, Vicari D, Thurmond JM, Lamb T, Mani A, Kane Y, Balint CR, Chalupa D, Otterson GA, Shapiro CL, Fowler JM, Grever MR, Bekaii-Saab TS, Carson WE 3rd. Kaumaya PT, et al. J Clin Oncol. 2009 Nov 1;27(31):5270-7. doi: 10.1200/JCO.2009.22.3883. Epub 2009 Sep 14. J Clin Oncol. 2009. PMID: 19752336 Free PMC article. Clinical Trial.
Insulin-like growth factor-1 receptor signaling increases the invasive potential of human epidermal growth factor receptor 2-overexpressing breast cancer cells via Src-focal adhesion kinase and forkhead box protein M1.
Sanabria-Figueroa E, Donnelly SM, Foy KC, Buss MC, Castellino RC, Paplomata E, Taliaferro-Smith L, Kaumaya PT, Nahta R. Sanabria-Figueroa E, et al. Among authors: kaumaya pt. Mol Pharmacol. 2015 Feb;87(2):150-61. doi: 10.1124/mol.114.095380. Epub 2014 Nov 12. Mol Pharmacol. 2015. PMID: 25391374 Free PMC article.
Phase I Immunotherapy Trial with Two Chimeric HER-2 B-Cell Peptide Vaccines Emulsified in Montanide ISA 720VG and Nor-MDP Adjuvant in Patients with Advanced Solid Tumors.
Bekaii-Saab T, Wesolowski R, Ahn DH, Wu C, Mortazavi A, Lustberg M, Ramaswamy B, Fowler J, Wei L, Overholser J, Kaumaya PTP. Bekaii-Saab T, et al. Among authors: kaumaya ptp. Clin Cancer Res. 2019 Jun 15;25(12):3495-3507. doi: 10.1158/1078-0432.CCR-18-3997. Epub 2019 Feb 25. Clin Cancer Res. 2019. PMID: 30804020 Free PMC article. Clinical Trial.
64 results