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Coordinated activation of c-Src and FOXM1 drives tumor cell proliferation and breast cancer progression.
Nandi I, Smith HW, Sanguin-Gendreau V, Ji L, Pacis A, Papavasiliou V, Zuo D, Nam S, Attalla SS, Kim SH, Lusson S, Kuasne H, Fortier AM, Savage P, Martinez Ramirez C, Park M, Katzenellenbogen JA, Katzenellenbogen BS, Muller WJ. Nandi I, et al. Among authors: katzenellenbogen bs, katzenellenbogen ja. J Clin Invest. 2023 Apr 3;133(7):e162324. doi: 10.1172/JCI162324. J Clin Invest. 2023. PMID: 36795481 Free PMC article.
Somatic estrogen receptor α mutations that induce dimerization promote receptor activity and breast cancer proliferation.
Irani S, Tan W, Li Q, Toy W, Jones C, Gadiya M, Marra A, Katzenellenbogen JA, Carlson KE, Katzenellenbogen BS, Karimi M, Segu Rajappachetty R, Del Priore IS, Reis-Filho JS, Shen Y, Chandarlapaty S. Irani S, et al. Among authors: katzenellenbogen ja. J Clin Invest. 2024 Jan 2;134(1):e163242. doi: 10.1172/JCI163242. J Clin Invest. 2024. PMID: 37883178 Free PMC article.
Reprogramming of endothelial gene expression by tamoxifen inhibits angiogenesis and ERα-negative tumor growth.
Fébrissy C, Adlanmerini M, Péqueux C, Boudou F, Buscato M, Gargaros A, Gilardi-Bresson S, Boriak K, Laurell H, Fontaine C, Katzenellenbogen BS, Katzenellenbogen JA, Guillermet-Guibert J, Arnal JF, Metivier R, Lenfant F. Fébrissy C, et al. Among authors: katzenellenbogen ja. Theranostics. 2024 Jan 1;14(1):249-264. doi: 10.7150/thno.87306. eCollection 2024. Theranostics. 2024. PMID: 38164151 Free PMC article.
Asymmetric Allostery in Estrogen Receptor-α Homodimers Drives Responses to the Ensemble of Estrogens in the Hormonal Milieu.
Min CK, Nwachukwu JC, Hou Y, Russo RJ, Papa A, Min J, Peng R, Kim SH, Ziegler Y, Rangarajan ES, Izard T, Katzenellenbogen BS, Katzenellenbogen JA, Nettles KW. Min CK, et al. Among authors: katzenellenbogen ja. bioRxiv [Preprint]. 2024 Apr 13:2024.04.10.588871. doi: 10.1101/2024.04.10.588871. bioRxiv. 2024. PMID: 38645081 Free PMC article. Preprint.
ESR1 F404 Mutations and Acquired Resistance to Fulvestrant in ESR1-Mutant Breast Cancer.
Kingston B, Pearson A, Herrera-Abreu MT, Sim LX, Cutts RJ, Shah H, Moretti L, Kilburn LS, Johnson H, Macpherson IR, Ring A, Bliss JM, Hou Y, Toy W, Katzenellenbogen JA, Chandarlapaty S, Turner NC. Kingston B, et al. Among authors: katzenellenbogen ja. Cancer Discov. 2024 Feb 8;14(2):274-289. doi: 10.1158/2159-8290.CD-22-1387. Cancer Discov. 2024. PMID: 37982575 Free PMC article.
Endothelial ERα promotes glucose tolerance by enhancing endothelial insulin transport to skeletal muscle.
Sacharidou A, Chambliss K, Peng J, Barrera J, Tanigaki K, Luby-Phelps K, Özdemir İ, Khan S, Sirsi SR, Kim SH, Katzenellenbogen BS, Katzenellenbogen JA, Kanchwala M, Sathe AA, Lemoff A, Xing C, Hoyt K, Mineo C, Shaul PW. Sacharidou A, et al. Among authors: katzenellenbogen ja. Nat Commun. 2023 Aug 17;14(1):4989. doi: 10.1038/s41467-023-40562-w. Nat Commun. 2023. PMID: 37591837 Free PMC article.
508 results