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Modeling T cell temporal response to cancer immunotherapy rationalizes development of combinatorial treatment protocols.
Nat Cancer. 2024 Mar 1. doi: 10.1038/s43018-024-00734-z. Online ahead of print.
Nat Cancer. 2024.
PMID: 38429414
Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma.
Kirschenbaum D, Xie K, Ingelfinger F, Katzenelenbogen Y, Abadie K, Look T, Sheban F, Phan TS, Li B, Zwicky P, Yofe I, David E, Mazuz K, Hou J, Chen Y, Shaim H, Shanley M, Becker S, Qian J, Colonna M, Ginhoux F, Rezvani K, Theis FJ, Yosef N, Weiss T, Weiner A, Amit I.
Kirschenbaum D, et al. Among authors: katzenelenbogen y.
Cell. 2024 Jan 4;187(1):149-165.e23. doi: 10.1016/j.cell.2023.11.032. Epub 2023 Dec 21.
Cell. 2024.
PMID: 38134933
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Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell-dependent regression of glioblastoma.
Look T, Puca E, Bühler M, Kirschenbaum D, De Luca R, Stucchi R, Ravazza D, Di Nitto C, Roth P, Katzenelenbogen Y, Weiner A, Rindlisbacher L, Becher B, Amit I, Weller M, Neri D, Hemmerle T, Weiss T.
Look T, et al. Among authors: katzenelenbogen y.
Sci Transl Med. 2023 May 24;15(697):eadf2281. doi: 10.1126/scitranslmed.adf2281. Epub 2023 May 24.
Sci Transl Med. 2023.
PMID: 37224228
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In Synergy: Optimizing CAR T Development and Personalizing Patient Care Using Single-Cell Technologies.
Barboy O, Katzenelenbogen Y, Shalita R, Amit I.
Barboy O, et al. Among authors: katzenelenbogen y.
Cancer Discov. 2023 Jul 7;13(7):1546-1555. doi: 10.1158/2159-8290.CD-23-0010.
Cancer Discov. 2023.
PMID: 37219074
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The transcriptional and regulatory identity of erythropoietin producing cells.
Kragesteen BK, Giladi A, David E, Halevi S, Geirsdóttir L, Lempke OM, Li B, Bapst AM, Xie K, Katzenelenbogen Y, Dahl SL, Sheban F, Gurevich-Shapiro A, Zada M, Phan TS, Avellino R, Wang SY, Barboy O, Shlomi-Loubaton S, Winning S, Markwerth PP, Dekalo S, Keren-Shaul H, Kedmi M, Sikora M, Fandrey J, Korneliussen TS, Prchal JT, Rosenzweig B, Yutkin V, Racimo F, Willerslev E, Gur C, Wenger RH, Amit I.
Kragesteen BK, et al. Among authors: katzenelenbogen y.
Nat Med. 2023 May;29(5):1191-1200. doi: 10.1038/s41591-023-02314-7. Epub 2023 Apr 27.
Nat Med. 2023.
PMID: 37106166
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Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting.
Salomon R, Rotem H, Katzenelenbogen Y, Weiner A, Cohen Saban N, Feferman T, Amit I, Dahan R.
Salomon R, et al. Among authors: katzenelenbogen y.
Nat Cancer. 2022 Mar;3(3):287-302. doi: 10.1038/s43018-022-00329-6. Epub 2022 Feb 21.
Nat Cancer. 2022.
PMID: 35190724
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Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer.
Katzenelenbogen Y, Sheban F, Yalin A, Yofe I, Svetlichnyy D, Jaitin DA, Bornstein C, Moshe A, Keren-Shaul H, Cohen M, Wang SY, Li B, David E, Salame TM, Weiner A, Amit I.
Katzenelenbogen Y, et al.
Cell. 2020 Aug 20;182(4):872-885.e19. doi: 10.1016/j.cell.2020.06.032. Epub 2020 Aug 11.
Cell. 2020.
PMID: 32783915
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