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De novo NAD+ synthesis enhances mitochondrial function and improves health.
Katsyuba E, Mottis A, Zietak M, De Franco F, van der Velpen V, Gariani K, Ryu D, Cialabrini L, Matilainen O, Liscio P, Giacchè N, Stokar-Regenscheit N, Legouis D, de Seigneux S, Ivanisevic J, Raffaelli N, Schoonjans K, Pellicciari R, Auwerx J. Katsyuba E, et al. Nature. 2018 Nov;563(7731):354-359. doi: 10.1038/s41586-018-0645-6. Epub 2018 Oct 24. Nature. 2018. PMID: 30356218 Free PMC article.
Mitonuclear protein imbalance as a conserved longevity mechanism.
Houtkooper RH, Mouchiroud L, Ryu D, Moullan N, Katsyuba E, Knott G, Williams RW, Auwerx J. Houtkooper RH, et al. Among authors: katsyuba e. Nature. 2013 May 23;497(7450):451-7. doi: 10.1038/nature12188. Nature. 2013. PMID: 23698443 Free PMC article.
Modulating NAD+ metabolism, from bench to bedside.
Katsyuba E, Auwerx J. Katsyuba E, et al. EMBO J. 2017 Sep 15;36(18):2670-2683. doi: 10.15252/embj.201797135. Epub 2017 Aug 7. EMBO J. 2017. PMID: 28784597 Free PMC article. Review.
α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis.
Pellicciari R, Liscio P, Giacchè N, De Franco F, Carotti A, Robertson J, Cialabrini L, Katsyuba E, Raffaelli N, Auwerx J. Pellicciari R, et al. Among authors: katsyuba e. J Med Chem. 2018 Feb 8;61(3):745-759. doi: 10.1021/acs.jmedchem.7b01254. Epub 2018 Jan 26. J Med Chem. 2018. PMID: 29345930
NAD+ homeostasis in health and disease.
Katsyuba E, Romani M, Hofer D, Auwerx J. Katsyuba E, et al. Nat Metab. 2020 Jan;2(1):9-31. doi: 10.1038/s42255-019-0161-5. Epub 2020 Jan 20. Nat Metab. 2020. PMID: 32694684 Review.
Protein acetylation in metabolism - metabolites and cofactors.
Menzies KJ, Zhang H, Katsyuba E, Auwerx J. Menzies KJ, et al. Among authors: katsyuba e. Nat Rev Endocrinol. 2016 Jan;12(1):43-60. doi: 10.1038/nrendo.2015.181. Epub 2015 Oct 27. Nat Rev Endocrinol. 2016. PMID: 26503676 Review.
Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease.
Gariani K, Ryu D, Menzies KJ, Yi HS, Stein S, Zhang H, Perino A, Lemos V, Katsyuba E, Jha P, Vijgen S, Rubbia-Brandt L, Kim YK, Kim JT, Kim KS, Shong M, Schoonjans K, Auwerx J. Gariani K, et al. Among authors: katsyuba e. J Hepatol. 2017 Jan;66(1):132-141. doi: 10.1016/j.jhep.2016.08.024. Epub 2016 Sep 20. J Hepatol. 2017. PMID: 27663419 Free article.
Niacin: an old lipid drug in a new NAD+ dress.
Romani M, Hofer DC, Katsyuba E, Auwerx J. Romani M, et al. Among authors: katsyuba e. J Lipid Res. 2019 Apr;60(4):741-746. doi: 10.1194/jlr.S092007. Epub 2019 Feb 19. J Lipid Res. 2019. PMID: 30782960 Free PMC article.
21 results