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A distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia.
Markov NS, Ren Z, Senkow KJ, Grant RA, Gao CA, Malsin ES, Sichizya L, Kihshen H, Helmin KA, Jovisic M, Arnold JM, Pérez-Leonor XG, Abdala-Valencia H, Swaminathan S, Nwaezeapu J, Kang M, Rasmussen L, Ozer EA, Lorenzo-Redondo R, Hultquist JF, Simons LM, Rios-Guzman E, Misharin AV, Wunderink RG, Budinger GRS, Singer BD, Morales-Nebreda L; NU SCRIPT Study Investigators. Markov NS, et al. Among authors: helmin ka. bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571479. doi: 10.1101/2023.12.13.571479. bioRxiv. 2023. PMID: 38168346 Free PMC article. Preprint.
AMP-activated protein kinase is necessary for Treg cell functional adaptation to microenvironmental stress.
Torres Acosta MA, Mambetsariev N, Reyes Flores CP, Helmin KA, Liu Q, Joudi AM, Morales-Nebreda L, Gurkan J, Cheng K, Abdala-Valencia H, Weinberg SE, Singer BD. Torres Acosta MA, et al. Among authors: helmin ka. bioRxiv [Preprint]. 2023 Dec 1:2023.11.29.568904. doi: 10.1101/2023.11.29.568904. bioRxiv. 2023. PMID: 38076988 Free PMC article. Preprint.
The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging.
McQuattie-Pimentel AC, Ren Z, Joshi N, Watanabe S, Stoeger T, Chi M, Lu Z, Sichizya L, Aillon RP, Chen CI, Soberanes S, Chen Z, Reyfman PA, Walter JM, Anekalla KR, Davis JM, Helmin KA, Runyan CE, Abdala-Valencia H, Nam K, Meliton AY, Winter DR, Morimoto RI, Mutlu GM, Bharat A, Perlman H, Gottardi CJ, Ridge KM, Chandel NS, Sznajder JI, Balch WE, Singer BD, Misharin AV, Budinger GRS. McQuattie-Pimentel AC, et al. Among authors: helmin ka. J Clin Invest. 2021 Feb 15;131(4):e140299. doi: 10.1172/JCI140299. J Clin Invest. 2021. PMID: 33586677 Free PMC article.
Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation.
Fang C, Wang Z, Han C, Safgren SL, Helmin KA, Adelman ER, Serafin V, Basso G, Eagen KP, Gaspar-Maia A, Figueroa ME, Singer BD, Ratan A, Ntziachristos P, Zang C. Fang C, et al. Among authors: helmin ka. Genome Biol. 2020 Sep 15;21(1):247. doi: 10.1186/s13059-020-02152-7. Genome Biol. 2020. PMID: 32933554 Free PMC article.
19 results