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Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease.
O'Donoghue ML, Rosenson RS, Gencer B, López JAG, Lepor NE, Baum SJ, Stout E, Gaudet D, Knusel B, Kuder JF, Ran X, Murphy SA, Wang H, Wu Y, Kassahun H, Sabatine MS; OCEAN(a)-DOSE Trial Investigators. O'Donoghue ML, et al. Among authors: kassahun h. N Engl J Med. 2022 Nov 17;387(20):1855-1864. doi: 10.1056/NEJMoa2211023. Epub 2022 Nov 6. N Engl J Med. 2022. PMID: 36342163 Free article. Clinical Trial.
Ancestral diversity in lipoprotein(a) studies helps address evidence gaps.
Lee MP, Dimos SF, Raffield LM, Wang Z, Ballou AF, Downie CG, Arehart CH, Correa A, de Vries PS, Du Z, Gignoux CR, Gordon-Larsen P, Guo X, Haessler J, Howard AG, Hu Y, Kassahun H, Kent ST, Lopez JAG, Monda KL, North KE, Peters U, Preuss MH, Rich SS, Rhodes SL, Yao J, Yarosh R, Tsai MY, Rotter JI, Kooperberg CL, Loos RJF, Ballantyne C, Avery CL, Graff M. Lee MP, et al. Among authors: kassahun h. Open Heart. 2023 Aug;10(2):e002382. doi: 10.1136/openhrt-2023-002382. Open Heart. 2023. PMID: 37648373 Free PMC article.
Transient eddy current analysis for a spiral gradient pulse.
Alsharafi SS, Kassahun HB, Badawi AM, El-Sharkawy AM. Alsharafi SS, et al. Among authors: kassahun hb. J Magn Reson. 2023 Aug;353:107495. doi: 10.1016/j.jmr.2023.107495. Epub 2023 Jun 2. J Magn Reson. 2023. PMID: 37315479
Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a).
Koren MJ, Moriarty PM, Baum SJ, Neutel J, Hernandez-Illas M, Weintraub HS, Florio M, Kassahun H, Melquist S, Varrieur T, Haldar SM, Sohn W, Wang H, Elliott-Davey M, Rock BM, Pei T, Homann O, Hellawell J, Watts GF. Koren MJ, et al. Among authors: kassahun h. Nat Med. 2022 Jan;28(1):96-103. doi: 10.1038/s41591-021-01634-w. Epub 2022 Jan 13. Nat Med. 2022. PMID: 35027752 Clinical Trial.
Determinants of Plaque Progression Despite Very Low Low-Density Lipoprotein-Cholesterol Levels With the PCSK9 Inhibitor, Evolocumab.
Honda S, Puri R, Anderson T, Kastelein JJP, Brennan DM, Kassahun H, Somaratne R, Wasserman SM, Nissen SE, Nicholls SJ. Honda S, et al. Among authors: kassahun h. JACC Cardiovasc Imaging. 2022 Apr;15(4):709-711. doi: 10.1016/j.jcmg.2021.11.014. Epub 2021 Dec 15. JACC Cardiovasc Imaging. 2022. PMID: 34922870 Free article. No abstract available.
Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology.
SenGupta T, Palikaras K, Esbensen YQ, Konstantinidis G, Galindo FJN, Achanta K, Kassahun H, Stavgiannoudaki I, Bohr VA, Akbari M, Gaare J, Tzoulis C, Tavernarakis N, Nilsen H. SenGupta T, et al. Among authors: kassahun h. Cell Rep. 2021 Sep 7;36(10):109668. doi: 10.1016/j.celrep.2021.109668. Cell Rep. 2021. PMID: 34496255 Free PMC article.
Erratum to "C-Reactive Protein Levels and Plaque Regression with Evolocumab: Insights From GLAGOV" [American Journal of Preventive Cardiology 3C (2020) 100091].
Nelson AJ, Puri R, Brennan DM, Anderson TJ, Cho L, Ballantyne CM, Kastelein JJ, Koenig W, Kassahun H, Somaratne RM, Wasserman SM, Nissen SE, Nicholls SJ. Nelson AJ, et al. Among authors: kassahun h. Am J Prev Cardiol. 2021 Feb 11;6:100153. doi: 10.1016/j.ajpc.2021.100153. eCollection 2021 Jun. Am J Prev Cardiol. 2021. PMID: 34374706 Free PMC article.
58 results