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The Stroke Preclinical Assessment Network: Rationale, Design, Feasibility, and Stage 1 Results.
Lyden PD, Bosetti F, Diniz MA, Rogatko A, Koenig JI, Lamb J, Nagarkatti KA, Cabeen RP, Hess DC, Kamat PK, Khan MB, Wood K, Dhandapani K, Arbab AS, Leira EC, Chauhan AK, Dhanesha N, Patel RB, Kumskova M, Thedens D, Morais A, Imai T, Qin T, Ayata C, Boisserand LSB, Herman AL, Beatty HE, Velazquez SE, Diaz-Perez S, Sanganahalli BG, Mihailovic JM, Hyder F, Sansing LH, Koehler RC, Lannon S, Shi Y, Karuppagounder SS, Bibic A, Akhter K, Aronowski J, McCullough LD, Chauhan A, Goh A; SPAN Investigators. Lyden PD, et al. Among authors: karuppagounder ss. Stroke. 2022 May;53(5):1802-1812. doi: 10.1161/STROKEAHA.121.038047. Epub 2022 Mar 31. Stroke. 2022. PMID: 35354299 Free PMC article. Clinical Trial.
Sulfhydration mediates neuroprotective actions of parkin.
Vandiver MS, Paul BD, Xu R, Karuppagounder S, Rao F, Snowman AM, Ko HS, Lee YI, Dawson VL, Dawson TM, Sen N, Snyder SH. Vandiver MS, et al. Nat Commun. 2013;4:1626. doi: 10.1038/ncomms2623. Nat Commun. 2013. PMID: 23535647 Free PMC article.
Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss.
Lee Y, Karuppagounder SS, Shin JH, Lee YI, Ko HS, Swing D, Jiang H, Kang SU, Lee BD, Kang HC, Kim D, Tessarollo L, Dawson VL, Dawson TM. Lee Y, et al. Among authors: karuppagounder ss. Nat Neurosci. 2013 Oct;16(10):1392-400. doi: 10.1038/nn.3500. Epub 2013 Aug 25. Nat Neurosci. 2013. PMID: 23974709 Free PMC article.
LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity.
Karuppagounder SS, Xiong Y, Lee Y, Lawless MC, Kim D, Nordquist E, Martin I, Ge P, Brahmachari S, Jhaldiyal A, Kumar M, Andrabi SA, Dawson TM, Dawson VL. Karuppagounder SS, et al. J Chem Neuroanat. 2016 Oct;76(Pt B):90-97. doi: 10.1016/j.jchemneu.2016.01.007. Epub 2016 Jan 22. J Chem Neuroanat. 2016. PMID: 26808467 Free PMC article.
93 results