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Plasma versus tissue tumor mutational burden as biomarkers of durvalumab plus tremelimumab response in patients with metastatic colorectal cancer in the CO.26 trial.
Loree JM, Titmuss E, Topham JT, Kennecke HF, Feilotter H, Virk S, Lee YS, Banks K, Quinn K, Karsan A, Renouf DJ, Jonker DJ, Tu D, O'Callaghan CJ, Chen EX. Loree JM, et al. Among authors: karsan a. Clin Cancer Res. 2024 May 10. doi: 10.1158/1078-0432.CCR-24-0268. Online ahead of print. Clin Cancer Res. 2024. PMID: 38727700
Translation efficiency driven by CNOT3 subunit of the CCR4-NOT complex promotes leukemogenesis.
Ghashghaei M, Liu Y, Ettles J, Bombaci G, Ramkumar N, Liu Z, Escano L, Miko SS, Kim Y, Waldron JA, Do K, MacPherson K, Yuen KA, Taibi T, Yue M, Arsalan A, Jin Z, Edin G, Karsan A, Morin GB, Kuchenbauer F, Perna F, Bushell M, Vu LP. Ghashghaei M, et al. Among authors: karsan a. Nat Commun. 2024 Mar 15;15(1):2340. doi: 10.1038/s41467-024-46665-2. Nat Commun. 2024. PMID: 38491013 Free PMC article.
Spatially Resolved Tumor Microenvironment Predicts Treatment Outcomes in Relapsed/Refractory Hodgkin Lymphoma.
Aoki T, Jiang A, Xu A, Yin Y, Gamboa A, Milne K, Takata K, Miyata-Takata T, Chung S, Rai S, Wu S, Warren M, Strong C, Goodyear T, Morris K, Chong LC, Hav M, Colombo AR, Telenius A, Boyle M, Ben-Neriah S, Power M, Gerrie AS, Weng AP, Karsan A, Roth A, Farinha P, Scott DW, Savage KJ, Nelson BH, Merchant A, Steidl C. Aoki T, et al. Among authors: karsan a. J Clin Oncol. 2024 Mar 20;42(9):1077-1087. doi: 10.1200/JCO.23.01115. Epub 2023 Dec 19. J Clin Oncol. 2024. PMID: 38113419 Free PMC article.
Shift of the insoluble content of the proteome in the aging mouse brain.
Molzahn C, Kuechler ER, Zemlyankina I, Nierves L, Ali T, Cole G, Wang J, Albu RF, Zhu M, Cashman NR, Gilch S, Karsan A, Lange PF, Gsponer J, Mayor T. Molzahn C, et al. Among authors: karsan a. Proc Natl Acad Sci U S A. 2023 Nov 7;120(45):e2310057120. doi: 10.1073/pnas.2310057120. Epub 2023 Oct 31. Proc Natl Acad Sci U S A. 2023. PMID: 37906643 Free PMC article.
"I just wanted more": Hereditary cancer syndromes patients' perspectives on the utility of circulating tumour DNA testing for cancer screening.
Adi-Wauran E, Clausen M, Shickh S, Gagliardi AR, Denburg A, Oldfield LE, Sam J, Reble E, Krishnapillai S, Regier DA, Baxter NN, Dawson L, Penney LS, Foulkes W, Basik M, Sun S, Schrader KA, Karsan A, Pollett A, Pugh TJ; CHARM consortium; Kim RH, Bombard Y. Adi-Wauran E, et al. Among authors: karsan a. Eur J Hum Genet. 2024 Feb;32(2):176-181. doi: 10.1038/s41431-023-01473-y. Epub 2023 Oct 11. Eur J Hum Genet. 2024. PMID: 37821757
222 results