Karpov VL - Search Results

1

Mutations conferring drug resistance affect eukaryotic expression of HIV type 1 reverse transcriptase.

Isaguliants MG, Belikov SV, Starodubova ES, Gizatullin RZ, Rollman E, Zuber B, Zuber AK, Grishchenko OI, Rytting AS, Källander CF, Kochetkov SN, Karpov VL, Wahren B. Isaguliants MG, et al. Among authors: karpov vl. AIDS Res Hum Retroviruses. 2004 Feb;20(2):191-201. doi: 10.1089/088922204773004914. AIDS Res Hum Retroviruses. 2004. PMID: 15018707

2

HIV-1 reverse transcriptase targeted for proteasomal degradation as a prototype vaccine against drug-resistant HIV-1.

Starodubova E, Boberg A, Kashuba EV, Wahren B, Karpov V, Isaguliants M. Starodubova E, et al. Vaccine. 2006 May 22;24(21):4541-7. doi: 10.1016/j.vaccine.2005.08.020. Epub 2005 Aug 18. Vaccine. 2006. PMID: 16181708

3

Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme's performance in gene immunization.

Isaguliants M, Smirnova O, Ivanov AV, Kilpelainen A, Kuzmenko Y, Petkov S, Latanova A, Krotova O, Engström G, Karpov V, Kochetkov S, Wahren B, Starodubova E. Isaguliants M, et al. Hum Vaccin Immunother. 2013 Oct;9(10):2111-9. doi: 10.4161/hv.25813. Epub 2013 Jul 23. Hum Vaccin Immunother. 2013. PMID: 23881028 Free PMC article.

4

HIV-1 reverse transcriptase artificially targeted for proteasomal degradation induces a mixed Th1/Th2-type immune response.

Starodubova ES, Boberg A, Litvina M, Morozov A, Petrakova NV, Timofeev A, Latyshev O, Tunitskaya V, Wahren B, Isaguliants MG, Karpov VL. Starodubova ES, et al. Among authors: karpov vl. Vaccine. 2008 Sep 19;26(40):5170-6. doi: 10.1016/j.vaccine.2008.03.070. Epub 2008 Apr 15. Vaccine. 2008. PMID: 18468738

5

Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity.

Latanova AA, Petkov S, Kilpelainen A, Jansons J, Latyshev OE, Kuzmenko YV, Hinkula J, Abakumov MA, Valuev-Elliston VT, Gomelsky M, Karpov VL, Chiodi F, Wahren B, Logunov DY, Starodubova ES, Isaguliants MG. Latanova AA, et al. Among authors: karpov vl. Sci Rep. 2018 May 24;8(1):8078. doi: 10.1038/s41598-018-26281-z. Sci Rep. 2018. PMID: 29799015 Free PMC article.

6

Potent cross-reactive immune response against the wild-type and drug-resistant forms of HIV reverse transcriptase after the chimeric gene immunization.

Starodubova E, Boberg A, Ivanov A, Latyshev O, Petrakova N, Kuzmenko Y, Litvina M, Chernousov A, Kochetkov S, Karpov V, Wahren B, Isaguliants MG. Starodubova E, et al. Vaccine. 2010 Feb 23;28(8):1975-86. doi: 10.1016/j.vaccine.2009.10.098. Vaccine. 2010. PMID: 20188253

7

Consensus HIV-1 subtype A integrase and its raltegravir-resistant variants: design and characterization of the enzymatic properties.

Shadrina O, Krotova O, Agapkina J, Knyazhanskaya E, Korolev S, Starodubova E, Viklund A, Lukashov V, Magnani M, Medstrand P, Karpov V, Gottikh M, Isaguliants M. Shadrina O, et al. Biochimie. 2014 Jul;102:92-101. doi: 10.1016/j.biochi.2014.02.013. Epub 2014 Mar 2. Biochimie. 2014. PMID: 24594066

8

Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Effects on Its Immunogenic Performance in DNA-Immunized Mice.

Latanova A, Petkov S, Kuzmenko Y, Kilpeläinen A, Ivanov A, Smirnova O, Krotova O, Korolev S, Hinkula J, Karpov V, Isaguliants M, Starodubova E. Latanova A, et al. J Immunol Res. 2017;2017:7407136. doi: 10.1155/2017/7407136. Epub 2017 Jun 22. J Immunol Res. 2017. PMID: 28717654 Free PMC article.

9

[Artifitial increase of HIV-1 reverse transcriptase turnover through proteasome pathway].

Starodubova ES, Isaguliants MG, Karpov VL. Starodubova ES, et al. Among authors: karpov vl. Mol Biol (Mosk). 2006 Nov-Dec;40(6):982-8. Mol Biol (Mosk). 2006. PMID: 17209425 Russian.

10

Fusion to the Lysosome Targeting Signal of the Invariant Chain Alters the Processing and Enhances the Immunogenicity of HIV-1 Reverse Transcriptase.

Starodubova ES, Isaguliants MG, Kuzmenko YV, Latanova AA, Krotova OA, Karpov VL. Starodubova ES, et al. Among authors: karpov vl. Acta Naturae. 2014 Jan;6(1):61-8. Acta Naturae. 2014. PMID: 24772328 Free PMC article.

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