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Spirocyclic dimer SpiD7 activates the unfolded protein response to selectively inhibit growth and induce apoptosis of cancer cells.
Kour S, Rana S, Kubica SP, Kizhake S, Ahmad M, Muñoz-Trujillo C, Klinkebiel D, Singh S, Mallareddy JR, Chandra S, Woods NT, Karpf AR, Natarajan A. Kour S, et al. Among authors: karpf ar. J Biol Chem. 2022 May;298(5):101890. doi: 10.1016/j.jbc.2022.101890. Epub 2022 Apr 1. J Biol Chem. 2022. PMID: 35378132 Free PMC article.
CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models.
Xu H, George E, Kinose Y, Kim H, Shah JB, Peake JD, Ferman B, Medvedev S, Murtha T, Barger CJ, Devins KM, D'Andrea K, Wubbenhorst B, Schwartz LE, Hwang WT, Mills GB, Nathanson KL, Karpf AR, Drapkin R, Brown EJ, Simpkins F. Xu H, et al. Among authors: karpf ar. Cell Rep Med. 2021 Sep 23;2(9):100394. doi: 10.1016/j.xcrm.2021.100394. eCollection 2021 Sep 21. Cell Rep Med. 2021. PMID: 34622231 Free PMC article.
Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer.
Barger CJ, Chee L, Albahrani M, Munoz-Trujillo C, Boghean L, Branick C, Odunsi K, Drapkin R, Zou L, Karpf AR. Barger CJ, et al. Among authors: karpf ar. Elife. 2021 Apr 23;10:e55070. doi: 10.7554/eLife.55070. Elife. 2021. PMID: 33890574 Free PMC article.
117 results