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The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities.
Venner E, Patterson K, Kalra D, Wheeler MM, Chen YJ, Kalla SE, Yuan B, Karnes JH, Walker K, Smith JD, McGee S, Radhakrishnan A, Haddad A, Empey PE, Wang Q, Lichtenstein L, Toledo D, Jarvik G, Musick A, Gibbs RA; All of Us Research Program Investigators. Venner E, et al. Among authors: karnes jh. Commun Biol. 2024 Feb 19;7(1):174. doi: 10.1038/s42003-023-05708-y. Commun Biol. 2024. PMID: 38374434 Free PMC article.
Identifying genetically driven clinical phenotypes using linear mixed models.
Mosley JD, Witte JS, Larkin EK, Bastarache L, Shaffer CM, Karnes JH, Stein CM, Phillips E, Hebbring SJ, Brilliant MH, Mayer J, Ye Z, Roden DM, Denny JC. Mosley JD, et al. Among authors: karnes jh. Nat Commun. 2016 Apr 25;7:11433. doi: 10.1038/ncomms11433. Nat Commun. 2016. PMID: 27109359 Free PMC article.
The "All of Us" Research Program.
All of Us Research Program Investigators; Denny JC, Rutter JL, Goldstein DB, Philippakis A, Smoller JW, Jenkins G, Dishman E. All of Us Research Program Investigators, et al. N Engl J Med. 2019 Aug 15;381(7):668-676. doi: 10.1056/NEJMsr1809937. N Engl J Med. 2019. PMID: 31412182 Free PMC article.
Approach to High Volume Enrollment in Clinical Research: Experiences from an All of Us Research Program Site.
Ilori TO, Viera E, Wilson J, Moreno F, Menon U, Ehiri J, Peterson R, Vemulapalli T, StimsonRiahi SC, Rosales C, Calhoun E, Sokan A, Karnes JH, Reiman E, Ojo A, Theodorou A, Ojo T. Ilori TO, et al. Among authors: karnes jh. Clin Transl Sci. 2020 Jul;13(4):685-692. doi: 10.1111/cts.12759. Epub 2020 Mar 17. Clin Transl Sci. 2020. PMID: 32004412 Free PMC article.
Comparison of family health history in surveys vs electronic health record data mapped to the observational medical outcomes partnership data model in the All of Us Research Program.
Cronin RM, Halvorson AE, Springer C, Feng X, Sulieman L, Loperena-Cortes R, Mayo K, Carroll RJ, Chen Q, Ahmedani BK, Karnes J, Korf B, O'Donnell CJ, Qian J, Ramirez AH. Cronin RM, et al. J Am Med Inform Assoc. 2021 Mar 18;28(4):695-703. doi: 10.1093/jamia/ocaa315. J Am Med Inform Assoc. 2021. PMID: 33404595 Free PMC article.
Racial, ethnic, and gender differences in obesity and body fat distribution: An All of Us Research Program demonstration project.
Karnes JH, Arora A, Feng J, Steiner HE, Sulieman L, Boerwinkle E, Clark C, Cicek M, Cohn E, Gebo K, Loperena-Cortes R, Ohno-Machado L, Mayo K, Mockrin S, Ramirez A, Schully S, Klimentidis YC. Karnes JH, et al. PLoS One. 2021 Aug 6;16(8):e0255583. doi: 10.1371/journal.pone.0255583. eCollection 2021. PLoS One. 2021. PMID: 34358277 Free PMC article.
Geographic Variation in Obesity at the State Level in the All of Us Research Program.
Clark CR, Chandler PD, Zhou G, Noel N, Achilike C, Mendez L, O'Connor GT, Smoller JW, Weiss ST, Murphy SN, Ommerborn MJ, Karnes JH, Klimentidis YC, Jordan CD, Hiatt RA, Ramirez AH, Loperena R, Mayo K, Cohn E, Ohno-Machado L, Boerwinkle E, Cicek M, Schully SD, Mockrin S, Gebo KA, Karlson EW. Clark CR, et al. Among authors: karnes jh. Prev Chronic Dis. 2021 Dec 23;18:E104. doi: 10.5888/pcd18.210094. Prev Chronic Dis. 2021. PMID: 34941480 Free PMC article.
A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers.
Mosley JD, Feng Q, Wells QS, Van Driest SL, Shaffer CM, Edwards TL, Bastarache L, Wei WQ, Davis LK, McCarty CA, Thompson W, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Verma SS, Karnes JH, Weiss ST, Wang TJ, Stein CM, Denny JC, Roden DM. Mosley JD, et al. Among authors: karnes jh. Nat Commun. 2018 Aug 30;9(1):3522. doi: 10.1038/s41467-018-05624-4. Nat Commun. 2018. PMID: 30166544 Free PMC article.
62 results