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Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses.
Moin SM, Boyington JC, Boyoglu-Barnum S, Gillespie RA, Cerutti G, Cheung CS, Cagigi A, Gallagher JR, Brand J, Prabhakaran M, Tsybovsky Y, Stephens T, Fisher BE, Creanga A, Ataca S, Rawi R, Corbett KS, Crank MC, Karlsson Hedestam GB, Gorman J, McDermott AB, Harris AK, Zhou T, Kwong PD, Shapiro L, Mascola JR, Graham BS, Kanekiyo M. Moin SM, et al. Among authors: karlsson hedestam gb. Immunity. 2022 Dec 13;55(12):2405-2418.e7. doi: 10.1016/j.immuni.2022.10.015. Epub 2022 Nov 9. Immunity. 2022. PMID: 36356572 Free PMC article.
A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha.
Siggs OM, Berger M, Krebs P, Arnold CN, Eidenschenk C, Huber C, Pirie E, Smart NG, Khovananth K, Xia Y, McInerney G, Karlsson Hedestam GB, Nemazee D, Beutler B. Siggs OM, et al. Among authors: karlsson hedestam gb. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3046-51. doi: 10.1073/pnas.0915098107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133626 Free PMC article.
A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.
Arnold CN, Pirie E, Dosenovic P, McInerney GM, Xia Y, Wang N, Li X, Siggs OM, Karlsson Hedestam GB, Beutler B. Arnold CN, et al. Among authors: karlsson hedestam gb. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12286-93. doi: 10.1073/pnas.1209134109. Epub 2012 Jul 3. Proc Natl Acad Sci U S A. 2012. PMID: 22761313 Free PMC article.
Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein.
Mörner A, Douagi I, Forsell MN, Sundling C, Dosenovic P, O'Dell S, Dey B, Kwong PD, Voss G, Thorstensson R, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Mörner A, et al. Among authors: karlsson hedestam gb. J Virol. 2009 Jan;83(2):540-51. doi: 10.1128/JVI.01102-08. Epub 2008 Nov 12. J Virol. 2009. PMID: 19004960 Free PMC article.
Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates.
Douagi I, Forsell MN, Sundling C, O'Dell S, Feng Y, Dosenovic P, Li Y, Seder R, Loré K, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Douagi I, et al. Among authors: karlsson hedestam gb. J Virol. 2010 Feb;84(4):1683-95. doi: 10.1128/JVI.01896-09. Epub 2009 Dec 2. J Virol. 2010. PMID: 19955308 Free PMC article.
Immunization with wild-type or CD4-binding-defective HIV-1 Env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus.
Sundling C, O'Dell S, Douagi I, Forsell MN, Mörner A, Loré K, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Sundling C, et al. Among authors: karlsson hedestam gb. J Virol. 2010 Sep;84(18):9086-95. doi: 10.1128/JVI.01015-10. Epub 2010 Jul 7. J Virol. 2010. PMID: 20610729 Free PMC article.
129 results