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Probing Biased Signaling in Chemokine Receptors.
Methods Enzymol. 2016;570:155-86. doi: 10.1016/bs.mie.2015.09.001. Epub 2015 Nov 14.
Methods Enzymol. 2016.
PMID: 26921946
Review.
Probing the Molecular Interactions between CXC Chemokine Receptor 4 (CXCR4) and an Arginine-Based Tripeptidomimetic Antagonist (KRH-1636).
Zachariassen ZG, Karlshøj S, Haug BE, Rosenkilde MM, Våbenø J.
Zachariassen ZG, et al. Among authors: karlshoj s.
J Med Chem. 2015 Oct 22;58(20):8141-53. doi: 10.1021/acs.jmedchem.5b00987. Epub 2015 Oct 2.
J Med Chem. 2015.
PMID: 26397724
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Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule Binding.
Barington L, Rummel PC, Lückmann M, Pihl H, Larsen O, Daugvilaite V, Johnsen AH, Frimurer TM, Karlshøj S, Rosenkilde MM.
Barington L, et al. Among authors: karlshoj s.
J Biol Chem. 2016 Jul 29;291(31):16208-20. doi: 10.1074/jbc.M115.706747. Epub 2016 May 19.
J Biol Chem. 2016.
PMID: 27226537
Free PMC article.
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Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5).
Karlshøj S, Amarandi RM, Larsen O, Daugvilaite V, Steen A, Brvar M, Pui A, Frimurer TM, Ulven T, Rosenkilde MM.
Karlshøj S, et al.
J Biol Chem. 2016 Dec 23;291(52):26860-26874. doi: 10.1074/jbc.M116.740183. Epub 2016 Nov 10.
J Biol Chem. 2016.
PMID: 27834679
Free PMC article.
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Influence of chain length on the activity of tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4).
Baumann M, Hussain MM, Henne N, Garrote DM, Karlshøj S, Fossen T, Rosenkilde MM, Våbenø J, Haug BE.
Baumann M, et al. Among authors: karlshoj s.
Bioorg Med Chem. 2017 Jan 15;25(2):646-657. doi: 10.1016/j.bmc.2016.11.036. Epub 2016 Nov 21.
Bioorg Med Chem. 2017.
PMID: 27939345
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Selective Allosteric Modulation of N-Terminally Cleaved, but Not Full Length CCL3 in CCR1.
Larsen O, Lückmann M, van der Velden WJC, Oliva-Santiago M, Brvar M, Ulven T, Frimurer TM, Karlshøj S, Rosenkilde MM.
Larsen O, et al. Among authors: karlshoj s.
ACS Pharmacol Transl Sci. 2019 Nov 13;2(6):429-441. doi: 10.1021/acsptsci.9b00059. eCollection 2019 Dec 13.
ACS Pharmacol Transl Sci. 2019.
PMID: 32259075
Free PMC article.
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Identification of a conserved chemokine receptor motif that enables ligand discrimination.
Larsen O, van der Velden WJC, Mavri M, Schuermans S, Rummel PC, Karlshøj S, Gustavsson M, Proost P, Våbenø J, Rosenkilde MM.
Larsen O, et al. Among authors: karlshoj s.
Sci Signal. 2022 Mar 8;15(724):eabg7042. doi: 10.1126/scisignal.abg7042. Epub 2022 Mar 8.
Sci Signal. 2022.
PMID: 35258997
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Identification of a Salt Bridge That Is Functionally Important for Chemokine Receptor CXCR1 but not CXCR2.
Våbenø J, Oliva-Santiago M, Jørgensen AS, Karlshøj S, Rosenkilde MM.
Våbenø J, et al. Among authors: karlshoj s.
ACS Pharmacol Transl Sci. 2023 Jul 14;6(8):1120-1128. doi: 10.1021/acsptsci.3c00070. eCollection 2023 Aug 11.
ACS Pharmacol Transl Sci. 2023.
PMID: 37588755
Free article.
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