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The C-BIG Repository: an Institution-Level Open Science Platform.
Das S, Abou-Haidar R, Rabalais H, Sun SDLW, Rosli Z, Chatpar K, Boivin MN, Tabatabaei M, Rogers C, Legault M, Lo D, Degroot C, Dagher A, Dyke SOM, Durcan TM, Seyller A, Doyon J, Poupon V, Fon EA, Genge A, Rouleau GA, Karamchandani J, Evans AC. Das S, et al. Among authors: karamchandani j. Neuroinformatics. 2022 Jan;20(1):139-153. doi: 10.1007/s12021-021-09516-9. Epub 2021 May 18. Neuroinformatics. 2022. PMID: 34003431 Free PMC article.
Cyberinfrastructure for Open Science at the Montreal Neurological Institute.
Das S, Glatard T, Rogers C, Saigle J, Paiva S, MacIntyre L, Safi-Harab M, Rousseau ME, Stirling J, Khalili-Mahani N, MacFarlane D, Kostopoulos P, Rioux P, Madjar C, Lecours-Boucher X, Vanamala S, Adalat R, Mohaddes Z, Fonov VS, Milot S, Leppert I, Degroot C, Durcan TM, Campbell T, Moreau J, Dagher A, Collins DL, Karamchandani J, Bar-Or A, Fon EA, Hoge R, Baillet S, Rouleau G, Evans AC. Das S, et al. Among authors: karamchandani j. Front Neuroinform. 2017 Jan 6;10:53. doi: 10.3389/fninf.2016.00053. eCollection 2016. Front Neuroinform. 2017. PMID: 28111547 Free PMC article.
The Quebec Parkinson Network: A Researcher-Patient Matching Platform and Multimodal Biorepository.
Gan-Or Z, Rao T, Leveille E, Degroot C, Chouinard S, Cicchetti F, Dagher A, Das S, Desautels A, Drouin-Ouellet J, Durcan T, Gagnon JF, Genge A, Karamchandani J, Lafontaine AL, Sun SLW, Langlois M, Levesque M, Melmed C, Panisset M, Parent M, Poline JB, Postuma RB, Pourcher E, Rouleau GA, Sharp M, Monchi O, Dupré N, Fon EA. Gan-Or Z, et al. Among authors: karamchandani j. J Parkinsons Dis. 2020;10(1):301-313. doi: 10.3233/JPD-191775. J Parkinsons Dis. 2020. PMID: 31868683 Free PMC article.
Generation of homozygous PRKN, PINK1 and double PINK1/PRKN knockout cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing.
Chen CX, You Z, Abdian N, Sirois J, Shlaifer I, Tabatabaei M, Boivin MN, Gaborieau L, Karamchandani J, Beitel LK, Fon EA, Durcan TM. Chen CX, et al. Among authors: karamchandani j. Stem Cell Res. 2022 Jul;62:102806. doi: 10.1016/j.scr.2022.102806. Epub 2022 May 4. Stem Cell Res. 2022. PMID: 35561458 Free article.
CAPTURE ALS: the comprehensive analysis platform to understand, remedy and eliminate ALS.
Picher-Martel V, Magnussen C, Blais M, Bubela T, Das S, Dionne A, Evans AC, Genge A, Greiner R, Iturria-Medina Y, Johnston W, Jones K, Kaneb H, Karamchandani J, Moradipoor S, Robertson J, Rogaeva E, Taylor DM, Vande Velde C, Yunusova Y, Zinman L, Kalra S, Dupré N. Picher-Martel V, et al. Among authors: karamchandani j. Amyotroph Lateral Scler Frontotemporal Degener. 2023 Feb;24(1-2):33-39. doi: 10.1080/21678421.2022.2041668. Epub 2022 Feb 23. Amyotroph Lateral Scler Frontotemporal Degener. 2023. PMID: 35195049
Generation of patient-derived pluripotent stem cell-lines and CRISPR modified isogenic controls with mutations in the Parkinson's associated GBA gene.
X-Q Chen C, Deneault E, Abdian N, You Z, Sirois J, Nicouleau M, Shlaifer I, Villegas L, Boivin MN, Gaborieau L, Karamchandani J, Beitel LK, Fon EA, Durcan TM. X-Q Chen C, et al. Among authors: karamchandani j. Stem Cell Res. 2022 Oct;64:102919. doi: 10.1016/j.scr.2022.102919. Epub 2022 Sep 15. Stem Cell Res. 2022. PMID: 36130446 Free article.
Midbrain organoids with an SNCA gene triplication model key features of synucleinopathy.
Mohamed NV, Sirois J, Ramamurthy J, Mathur M, Lépine P, Deneault E, Maussion G, Nicouleau M, Chen CX, Abdian N, Soubannier V, Cai E, Nami H, Thomas RA, Wen D, Tabatabaei M, Beitel LK, Singh Dolt K, Karamchandani J, Stratton JA, Kunath T, Fon EA, Durcan TM. Mohamed NV, et al. Among authors: karamchandani j. Brain Commun. 2021 Sep 25;3(4):fcab223. doi: 10.1093/braincomms/fcab223. eCollection 2021. Brain Commun. 2021. PMID: 34632384 Free PMC article.
Recessive mutations in VPS13D cause childhood onset movement disorders.
Gauthier J, Meijer IA, Lessel D, Mencacci NE, Krainc D, Hempel M, Tsiakas K, Prokisch H, Rossignol E, Helm MH, Rodan LH, Karamchandani J, Carecchio M, Lubbe SJ, Telegrafi A, Henderson LB, Lorenzo K, Wallace SE, Glass IA, Hamdan FF, Michaud JL, Rouleau GA, Campeau PM. Gauthier J, et al. Among authors: karamchandani j. Ann Neurol. 2018 Jun;83(6):1089-1095. doi: 10.1002/ana.25204. Epub 2018 Apr 10. Ann Neurol. 2018. PMID: 29518281
88 results