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Inhibiting the stringent response blocks Mycobacterium tuberculosis entry into quiescence and reduces persistence.
Dutta NK, Klinkenberg LG, Vazquez MJ, Segura-Carro D, Colmenarejo G, Ramon F, Rodriguez-Miquel B, Mata-Cantero L, Porras-De Francisco E, Chuang YM, Rubin H, Lee JJ, Eoh H, Bader JS, Perez-Herran E, Mendoza-Losana A, Karakousis PC. Dutta NK, et al. Among authors: karakousis pc. Sci Adv. 2019 Mar 20;5(3):eaav2104. doi: 10.1126/sciadv.aav2104. eCollection 2019 Mar. Sci Adv. 2019. PMID: 30906866 Free PMC article.
Accelerated detection of Mycobacterium tuberculosis genes essential for bacterial survival in guinea pigs, compared with mice.
Jain SK, Hernandez-Abanto SM, Cheng QJ, Singh P, Ly LH, Klinkenberg LG, Morrison NE, Converse PJ, Nuermberger E, Grosset J, McMurray DN, Karakousis PC, Lamichhane G, Bishai WR. Jain SK, et al. Among authors: karakousis pc. J Infect Dis. 2007 Jun 1;195(11):1634-42. doi: 10.1086/517526. Epub 2007 Apr 23. J Infect Dis. 2007. PMID: 17471433
Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models.
Converse PJ, Karakousis PC, Klinkenberg LG, Kesavan AK, Ly LH, Allen SS, Grosset JH, Jain SK, Lamichhane G, Manabe YC, McMurray DN, Nuermberger EL, Bishai WR. Converse PJ, et al. Among authors: karakousis pc. Infect Immun. 2009 Mar;77(3):1230-7. doi: 10.1128/IAI.01117-08. Epub 2008 Dec 22. Infect Immun. 2009. PMID: 19103767 Free PMC article.
The impact of mouse passaging of Mycobacterium tuberculosis strains prior to virulence testing in the mouse and guinea pig aerosol models.
Converse PJ, Eisenach KD, Theus SA, Nuermberger EL, Tyagi S, Ly LH, Geiman DE, Guo H, Nolan ST, Akar NC, Klinkenberg LG, Gupta R, Lun S, Karakousis PC, Lamichhane G, McMurray DN, Grosset JH, Bishai WR. Converse PJ, et al. Among authors: karakousis pc. PLoS One. 2010 Apr 21;5(4):e10289. doi: 10.1371/journal.pone.0010289. PLoS One. 2010. PMID: 20422019 Free PMC article.
145 results