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A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques.
Van Rompay KKA, Coffey LL, Kapoor T, Gazumyan A, Keesler RI, Jurado A, Peace A, Agudelo M, Watanabe J, Usachenko J, Singapuri A, Immareddy R, Ardeshir A, Stuart JB, Bournazos S, Ravetch JV, Balderes PJ, Lorenz IC, Esswein SR, Keeffe JR, Bjorkman PJ, Wang Q, Rice CM, MacDonald MR, Nussenzweig MC, Robbiani DF. Van Rompay KKA, et al. Among authors: kapoor t. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7981-7989. doi: 10.1073/pnas.2000414117. Epub 2020 Mar 24. Proc Natl Acad Sci U S A. 2020. PMID: 32209664 Free PMC article.
Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
Agudelo M, Palus M, Keeffe JR, Bianchini F, Svoboda P, Salát J, Peace A, Gazumyan A, Cipolla M, Kapoor T, Guidetti F, Yao KH, Elsterová J, Teislerová D, Chrdle A, Hönig V, Oliveira T, West AP, Lee YE, Rice CM, MacDonald MR, Bjorkman PJ, Růžek D, Robbiani DF, Nussenzweig MC. Agudelo M, et al. Among authors: kapoor t. J Exp Med. 2021 May 3;218(5):e20210236. doi: 10.1084/jem.20210236. J Exp Med. 2021. PMID: 33831141 Free PMC article.
Prevalence of Powassan Virus Seropositivity Among People with History of Lyme Disease and Non-Lyme Community Controls in the Northeastern United States.
Kapoor T, Murray L, Kuvaldina M, Jiang CS, Peace AA, Agudelo M, Jurado A, Robbiani DF, Klemens O, Lattwein E, Sabalza M, Fallon BA, MacDonald MR. Kapoor T, et al. Vector Borne Zoonotic Dis. 2024 Apr;24(4):226-236. doi: 10.1089/vbz.2022.0030. Epub 2024 Mar 1. Vector Borne Zoonotic Dis. 2024. PMID: 38436222
Structure of the γ-tubulin ring complex-capped microtubule.
Aher A, Urnavicius L, Xue A, Neselu K, Kapoor TM. Aher A, et al. Among authors: kapoor tm. Nat Struct Mol Biol. 2024 Apr 12. doi: 10.1038/s41594-024-01264-z. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38609661
Using a Function-First "Scout Fragment"-Based Approach to Develop Allosteric Covalent Inhibitors of Conformationally Dynamic Helicase Mechanoenzymes.
Ramsey JR, Shelton PMM, Heiss TK, Olinares PDB, Vostal LE, Soileau H, Grasso M, Casebeer SW, Adaniya S, Miller M, Sun S, Huggins DJ, Myers RW, Chait BT, Vinogradova EV, Kapoor TM. Ramsey JR, et al. Among authors: kapoor tm. J Am Chem Soc. 2024 Jan 10;146(1):62-67. doi: 10.1021/jacs.3c10581. Epub 2023 Dec 22. J Am Chem Soc. 2024. PMID: 38134034
Structure of the γ-tubulin ring complex-capped microtubule.
Aher A, Urnavicius L, Xue A, Neselu K, Kapoor TM. Aher A, et al. Among authors: kapoor tm. bioRxiv [Preprint]. 2023 Nov 20:2023.11.20.567916. doi: 10.1101/2023.11.20.567916. bioRxiv. 2023. PMID: 38045257 Free PMC article. Updated. Preprint.
Using a function-first 'scout fragment'-based approach to develop allosteric covalent inhibitors of conformationally dynamic helicase mechanoenzymes.
Ramsey JR, Shelton PMM, Heiss TK, Olinares PDB, Vostal LE, Soileau H, Grasso M, Warrington S, Adaniya S, Miller M, Sun S, Huggins DJ, Myers RW, Chait BT, Vinogradova EV, Kapoor TM. Ramsey JR, et al. Among authors: kapoor tm. bioRxiv [Preprint]. 2023 Sep 26:2023.09.25.559391. doi: 10.1101/2023.09.25.559391. bioRxiv. 2023. PMID: 37808863 Free PMC article. Updated. Preprint.
198 results