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Global analysis of RNA-binding proteins identifies a positive feedback loop between LARP1 and MYC that promotes tumorigenesis.
Desi N, Tong QY, Teh V, Chan JJ, Zhang B, Tabatabaeian H, Tan HQ, Kapeli K, Jin W, Lim CY, Kwok ZH, Tan HT, Wang S, Siew BE, Lee KC, Chong CS, Tan KK, Yang H, Kappei D, Yeo GW, Chung MCM, Tay Y. Desi N, et al. Among authors: kapeli k. Cell Mol Life Sci. 2022 Feb 23;79(3):147. doi: 10.1007/s00018-021-04093-1. Cell Mol Life Sci. 2022. PMID: 35195778 Free PMC article.
LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance.
Wilbert ML, Huelga SC, Kapeli K, Stark TJ, Liang TY, Chen SX, Yan BY, Nathanson JL, Hutt KR, Lovci MT, Kazan H, Vu AQ, Massirer KB, Morris Q, Hoon S, Yeo GW. Wilbert ML, et al. Among authors: kapeli k. Mol Cell. 2012 Oct 26;48(2):195-206. doi: 10.1016/j.molcel.2012.08.004. Epub 2012 Sep 6. Mol Cell. 2012. PMID: 22959275 Free PMC article.
Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses.
Kapeli K, Pratt GA, Vu AQ, Hutt KR, Martinez FJ, Sundararaman B, Batra R, Freese P, Lambert NJ, Huelga SC, Chun SJ, Liang TY, Chang J, Donohue JP, Shiue L, Zhang J, Zhu H, Cambi F, Kasarskis E, Hoon S, Ares M Jr, Burge CB, Ravits J, Rigo F, Yeo GW. Kapeli K, et al. Nat Commun. 2016 Jul 5;7:12143. doi: 10.1038/ncomms12143. Nat Commun. 2016. PMID: 27378374 Free PMC article.
Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System.
Martinez FJ, Pratt GA, Van Nostrand EL, Batra R, Huelga SC, Kapeli K, Freese P, Chun SJ, Ling K, Gelboin-Burkhart C, Fijany L, Wang HC, Nussbacher JK, Broski SM, Kim HJ, Lardelli R, Sundararaman B, Donohue JP, Javaherian A, Lykke-Andersen J, Finkbeiner S, Bennett CF, Ares M Jr, Burge CB, Taylor JP, Rigo F, Yeo GW. Martinez FJ, et al. Among authors: kapeli k. Neuron. 2016 Nov 23;92(4):780-795. doi: 10.1016/j.neuron.2016.09.050. Epub 2016 Oct 20. Neuron. 2016. PMID: 27773581 Free PMC article.
Tissue-selective restriction of RNA editing of CaV1.3 by splicing factor SRSF9.
Huang H, Kapeli K, Jin W, Wong YP, Arumugam TV, Koh JH, Srimasorn S, Mallilankaraman K, Chua JJE, Yeo GW, Soong TW. Huang H, et al. Among authors: kapeli k. Nucleic Acids Res. 2018 Aug 21;46(14):7323-7338. doi: 10.1093/nar/gky348. Nucleic Acids Res. 2018. PMID: 29733375 Free PMC article.
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.
Ling SC, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan SH, Tse TM, Chang JC, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, McAlonis-Downes M, Han JS, Swing D, Kapeli K, Yeo GW, Tessarollo L, Marsala M, Shaw CE, Tucker-Kellogg G, La Spada AR, Lagier-Tourenne C, Da Cruz S, Cleveland DW. Ling SC, et al. Among authors: kapeli k. Elife. 2019 Feb 12;8:e40811. doi: 10.7554/eLife.40811. Elife. 2019. PMID: 30747709 Free PMC article.
12 results