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SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα.
Naiman S, Huynh FK, Gil R, Glick Y, Shahar Y, Touitou N, Nahum L, Avivi MY, Roichman A, Kanfi Y, Gertler AA, Doniger T, Ilkayeva OR, Abramovich I, Yaron O, Lerrer B, Gottlieb E, Harris RA, Gerber D, Hirschey MD, Cohen HY. Naiman S, et al. Among authors: kanfi y. Cell Rep. 2019 Dec 17;29(12):4127-4143.e8. doi: 10.1016/j.celrep.2019.11.067. Cell Rep. 2019. PMID: 31851938 Free PMC article.
Multiple regulatory layers of SREBP1/2 by SIRT6.
Elhanati S, Kanfi Y, Varvak A, Roichman A, Carmel-Gross I, Barth S, Gibor G, Cohen HY. Elhanati S, et al. Among authors: kanfi y. Cell Rep. 2013 Sep 12;4(5):905-12. doi: 10.1016/j.celrep.2013.08.006. Epub 2013 Sep 5. Cell Rep. 2013. PMID: 24012758 Free article.
Restoration of energy homeostasis by SIRT6 extends healthy lifespan.
Roichman A, Elhanati S, Aon MA, Abramovich I, Di Francesco A, Shahar Y, Avivi MY, Shurgi M, Rubinstein A, Wiesner Y, Shuchami A, Petrover Z, Lebenthal-Loinger I, Yaron O, Lyashkov A, Ubaida-Mohien C, Kanfi Y, Lerrer B, Fernández-Marcos PJ, Serrano M, Gottlieb E, de Cabo R, Cohen HY. Roichman A, et al. Among authors: kanfi y. Nat Commun. 2021 May 28;12(1):3208. doi: 10.1038/s41467-021-23545-7. Nat Commun. 2021. PMID: 34050173 Free PMC article.
The sirtuin SIRT6 regulates lifespan in male mice.
Kanfi Y, Naiman S, Amir G, Peshti V, Zinman G, Nahum L, Bar-Joseph Z, Cohen HY. Kanfi Y, et al. Nature. 2012 Feb 22;483(7388):218-21. doi: 10.1038/nature10815. Nature. 2012. PMID: 22367546
Sirtuins as regulators of mammalian aging.
Naiman S, Kanfi Y, Cohen HY. Naiman S, et al. Among authors: kanfi y. Aging (Albany NY). 2012 Aug;4(8):521-2. doi: 10.18632/aging.100478. Aging (Albany NY). 2012. PMID: 22915706 Free PMC article. No abstract available.
SIRT6 exhibits nucleosome-dependent deacetylase activity.
Gil R, Barth S, Kanfi Y, Cohen HY. Gil R, et al. Among authors: kanfi y. Nucleic Acids Res. 2013 Oct;41(18):8537-45. doi: 10.1093/nar/gkt642. Epub 2013 Jul 26. Nucleic Acids Res. 2013. PMID: 23892288 Free PMC article.
Characterization of physiological defects in adult SIRT6-/- mice.
Peshti V, Obolensky A, Nahum L, Kanfi Y, Rathaus M, Avraham M, Tinman S, Alt FW, Banin E, Cohen HY. Peshti V, et al. Among authors: kanfi y. PLoS One. 2017 Apr 27;12(4):e0176371. doi: 10.1371/journal.pone.0176371. eCollection 2017. PLoS One. 2017. PMID: 28448551 Free PMC article.
Sirtuin 6 protects the heart from hypoxic damage.
Maksin-Matveev A, Kanfi Y, Hochhauser E, Isak A, Cohen HY, Shainberg A. Maksin-Matveev A, et al. Among authors: kanfi y. Exp Cell Res. 2015 Jan 1;330(1):81-90. doi: 10.1016/j.yexcr.2014.07.013. Epub 2014 Jul 24. Exp Cell Res. 2015. PMID: 25066211
19 results