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Page 1
The Landscape of Atypical and Eukaryotic Protein Kinases.
Kanev GK, de Graaf C, de Esch IJP, Leurs R, Würdinger T, Westerman BA, Kooistra AJ. Kanev GK, et al. Trends Pharmacol Sci. 2019 Nov;40(11):818-832. doi: 10.1016/j.tips.2019.09.002. Epub 2019 Oct 31. Trends Pharmacol Sci. 2019. PMID: 31677919 Free article. Review.
KLIFS: a structural kinase-ligand interaction database.
Kooistra AJ, Kanev GK, van Linden OP, Leurs R, de Esch IJ, de Graaf C. Kooistra AJ, et al. Among authors: kanev gk. Nucleic Acids Res. 2016 Jan 4;44(D1):D365-71. doi: 10.1093/nar/gkv1082. Epub 2015 Oct 22. Nucleic Acids Res. 2016. PMID: 26496949 Free PMC article.
Crowdsourced mapping of unexplored target space of kinase inhibitors.
Cichońska A, Ravikumar B, Allaway RJ, Wan F, Park S, Isayev O, Li S, Mason M, Lamb A, Tanoli Z, Jeon M, Kim S, Popova M, Capuzzi S, Zeng J, Dang K, Koytiger G, Kang J, Wells CI, Willson TM; IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium; Oprea TI, Schlessinger A, Drewry DH, Stolovitzky G, Wennerberg K, Guinney J, Aittokallio T. Cichońska A, et al. Nat Commun. 2021 Jun 3;12(1):3307. doi: 10.1038/s41467-021-23165-1. Nat Commun. 2021. PMID: 34083538 Free PMC article.
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.
Menden MP, Wang D, Mason MJ, Szalai B, Bulusu KC, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M; AstraZeneca-Sanger Drug Combination DREAM Consortium; Jang IS, Ghazoui Z, Ahsen ME, Vogel R, Neto EC, Norman T, Tang EKY, Garnett MJ, Veroli GYD, Fawell S, Stolovitzky G, Guinney J, Dry JR, Saez-Rodriguez J. Menden MP, et al. Nat Commun. 2019 Jun 17;10(1):2674. doi: 10.1038/s41467-019-09799-2. Nat Commun. 2019. PMID: 31209238 Free PMC article.
To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?
Zheng Y, Schroeder S, Kanev GK, Botros SS, William S, Sabra AA, Maes L, Caljon G, Gil C, Martinez A, Salado IG, Augustyns K, Edink E, Sijm M, de Heuvel E, de Esch IJP, van der Meer T, Siderius M, Sterk GJ, Brown D, Leurs R. Zheng Y, et al. Among authors: kanev gk. Int J Mol Sci. 2023 Apr 6;24(7):6817. doi: 10.3390/ijms24076817. Int J Mol Sci. 2023. PMID: 37047792 Free PMC article.
A Real-world Toxicity Atlas Shows that Adverse Events of Combination Therapies Commonly Result in Additive Interactions.
Küçükosmanoglu A, Scoarta S, Houweling M, Spinu N, Wijnands T, Geerdink N, Meskers C, Kanev GK, Kiewiet B, Kouwenhoven M, Noske D, Wurdinger T, Pouwer M, Wolff M, Westerman BA. Küçükosmanoglu A, et al. Among authors: kanev gk. Clin Cancer Res. 2024 Apr 15;30(8):1685-1695. doi: 10.1158/1078-0432.CCR-23-0914. Clin Cancer Res. 2024. PMID: 38597991 Free PMC article.