Kamp F - Search Results

1

Modulating Hinge Flexibility in the APP Transmembrane Domain Alters γ-Secretase Cleavage.

Götz A, Mylonas N, Högel P, Silber M, Heinel H, Menig S, Vogel A, Feyrer H, Huster D, Luy B, Langosch D, Scharnagl C, Muhle-Goll C, Kamp F, Steiner H. Götz A, et al. Among authors: kamp f. Biophys J. 2019 Jun 4;116(11):2103-2120. doi: 10.1016/j.bpj.2019.04.030. Epub 2019 May 3. Biophys J. 2019. PMID: 31130234 Free PMC article.

2

Intramembrane proteolysis of β-amyloid precursor protein by γ-secretase is an unusually slow process.

Kamp F, Winkler E, Trambauer J, Ebke A, Fluhrer R, Steiner H. Kamp F, et al. Biophys J. 2015 Mar 10;108(5):1229-37. doi: 10.1016/j.bpj.2014.12.045. Biophys J. 2015. PMID: 25762334 Free PMC article.

3

Bexarotene Binds to the Amyloid Precursor Protein Transmembrane Domain, Alters Its α-Helical Conformation, and Inhibits γ-Secretase Nonselectively in Liposomes.

Kamp F, Scheidt HA, Winkler E, Basset G, Heinel H, Hutchison JM, LaPointe LM, Sanders CR, Steiner H, Huster D. Kamp F, et al. ACS Chem Neurosci. 2018 Jul 18;9(7):1702-1713. doi: 10.1021/acschemneuro.8b00068. Epub 2018 May 11. ACS Chem Neurosci. 2018. PMID: 29717863 Free PMC article.

4

Generation of Alzheimer disease-associated amyloid β42/43 peptide by γ-secretase can be inhibited directly by modulation of membrane thickness.

Winkler E, Kamp F, Scheuring J, Ebke A, Fukumori A, Steiner H. Winkler E, et al. Among authors: kamp f. J Biol Chem. 2012 Jun 15;287(25):21326-34. doi: 10.1074/jbc.M112.356659. Epub 2012 Apr 24. J Biol Chem. 2012. PMID: 22532566 Free PMC article.

5

The Nicastrin ectodomain adopts a highly thermostable structure.

Fluhrer R, Kamp F, Grammer G, Nuscher B, Steiner H, Beyer K, Haass C. Fluhrer R, et al. Among authors: kamp f. Biol Chem. 2011 Nov;392(11):995-1001. doi: 10.1515/BC.2011.169. Biol Chem. 2011. PMID: 21848507

6

Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms.

Mitterreiter S, Page RM, Kamp F, Hopson J, Winkler E, Ha HR, Hamid R, Herms J, Mayer TU, Nelson DJ, Steiner H, Stahl T, Zeitschel U, Rossner S, Haass C, Lichtenthaler SF. Mitterreiter S, et al. Among authors: kamp f. J Neurosci. 2010 Jun 30;30(26):8974-83. doi: 10.1523/JNEUROSCI.1199-10.2010. J Neurosci. 2010. PMID: 20592218 Free PMC article.

7

Photo-controlled delivery of very long chain fatty acids to cell membranes and modulation of membrane protein function.

Kong L, Dawkins E, Campbell F, Winkler E, Derks RJE, Giera M, Kamp F, Steiner H, Kros A. Kong L, et al. Among authors: kamp f. Biochim Biophys Acta Biomembr. 2020 May 1;1862(5):183200. doi: 10.1016/j.bbamem.2020.183200. Epub 2020 Jan 20. Biochim Biophys Acta Biomembr. 2020. PMID: 31972163 Free article.

8

Effective sample preparation procedure for the analysis of free neutral steroids, free steroid acids and sterol sulfates in different tissues by GC-MS.

Junker J, Kamp F, Winkler E, Steiner H, Bracher F, Müller C. Junker J, et al. Among authors: kamp f. J Steroid Biochem Mol Biol. 2021 Jul;211:105880. doi: 10.1016/j.jsbmb.2021.105880. Epub 2021 Mar 20. J Steroid Biochem Mol Biol. 2021. PMID: 33757894

9

Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol.

Junker J, Chong I, Kamp F, Steiner H, Giera M, Müller C, Bracher F. Junker J, et al. Among authors: kamp f. Molecules. 2019 Jun 26;24(13):2353. doi: 10.3390/molecules24132353. Molecules. 2019. PMID: 31247920 Free PMC article.

10

Inhibition of amyloid-β plaque formation by α-synuclein.

Bachhuber T, Katzmarski N, McCarter JF, Loreth D, Tahirovic S, Kamp F, Abou-Ajram C, Nuscher B, Serrano-Pozo A, Müller A, Prinz M, Steiner H, Hyman BT, Haass C, Meyer-Luehmann M. Bachhuber T, et al. Among authors: kamp f. Nat Med. 2015 Jul;21(7):802-7. doi: 10.1038/nm.3885. Epub 2015 Jun 22. Nat Med. 2015. PMID: 26099047

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