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Regulation of the cytochrome P450 epoxyeicosanoid pathway is associated with distinct histologic features in pediatric non-alcoholic fatty liver disease.
Kalveram L, Schunck WH, Rothe M, Rudolph B, Loddenkemper C, Holzhütter HG, Henning S, Bufler P, Schulz M, Meierhofer D, Zhang IW, Weylandt KH, Wiegand S, Hudert CA. Kalveram L, et al. Prostaglandins Leukot Essent Fatty Acids. 2021 Jan;164:102229. doi: 10.1016/j.plefa.2020.102229. Epub 2020 Dec 17. Prostaglandins Leukot Essent Fatty Acids. 2021. PMID: 33388475 Clinical Trial.
Noninvasive scores are poorly predictive of histological fibrosis in paediatric fatty liver disease.
Kalveram L, Baumann U, De Bruyne R, Draijer L, Janczyk W, Kelly D, Koot BG, Lacaille F, Lefere S, Lev HM, Lubrecht J, Mann JP, Mosca A, Rajwal S, Socha P, Vreugdenhil A, Alisi A, Hudert CA; ESPGHAN Fatty Liver Special Interest Group. Kalveram L, et al. J Pediatr Gastroenterol Nutr. 2024 Jan;78(1):27-35. doi: 10.1002/jpn3.12068. Epub 2023 Dec 29. J Pediatr Gastroenterol Nutr. 2024. PMID: 38291699