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Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression.
Ruivo CF, Bastos N, Adem B, Batista I, Duraes C, Melo CA, Castaldo SA, Campos-Laborie F, Moutinho-Ribeiro P, Morão B, Costa-Pinto A, Silva S, Osorio H, Ciordia S, Costa JL, Goodrich D, Cavadas B, Pereira L, Kouzarides T, Macedo G, Maio R, Carneiro F, Cravo M, Kalluri R, Machado JC, Melo SA. Ruivo CF, et al. Among authors: kalluri r. Gut. 2022 Jan 10;71(10):2043-68. doi: 10.1136/gutjnl-2021-324994. Online ahead of print. Gut. 2022. PMID: 35012996 Free PMC article.
Molecular pathways: microRNAs as cancer therapeutics.
Melo SA, Kalluri R. Melo SA, et al. Among authors: kalluri r. Clin Cancer Res. 2012 Aug 15;18(16):4234-9. doi: 10.1158/1078-0432.CCR-11-2010. Epub 2012 Jun 18. Clin Cancer Res. 2012. PMID: 22711704 Free PMC article. Review.
eRNAs are required for p53-dependent enhancer activity and gene transcription.
Melo CA, Drost J, Wijchers PJ, van de Werken H, de Wit E, Oude Vrielink JA, Elkon R, Melo SA, Léveillé N, Kalluri R, de Laat W, Agami R. Melo CA, et al. Among authors: kalluri r. Mol Cell. 2013 Feb 7;49(3):524-35. doi: 10.1016/j.molcel.2012.11.021. Epub 2012 Dec 27. Mol Cell. 2013. PMID: 23273978 Free article.
Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer.
Kahlert C, Melo SA, Protopopov A, Tang J, Seth S, Koch M, Zhang J, Weitz J, Chin L, Futreal A, Kalluri R. Kahlert C, et al. Among authors: kalluri r. J Biol Chem. 2014 Feb 14;289(7):3869-75. doi: 10.1074/jbc.C113.532267. Epub 2014 Jan 7. J Biol Chem. 2014. PMID: 24398677 Free PMC article. Clinical Trial.
Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis.
Melo SA, Sugimoto H, O'Connell JT, Kato N, Villanueva A, Vidal A, Qiu L, Vitkin E, Perelman LT, Melo CA, Lucci A, Ivan C, Calin GA, Kalluri R. Melo SA, et al. Among authors: kalluri r. Cancer Cell. 2014 Nov 10;26(5):707-21. doi: 10.1016/j.ccell.2014.09.005. Epub 2014 Oct 23. Cancer Cell. 2014. PMID: 25446899 Free PMC article.
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer.
Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R. Melo SA, et al. Among authors: kalluri r. Nature. 2015 Jul 9;523(7559):177-82. doi: 10.1038/nature14581. Epub 2015 Jun 24. Nature. 2015. PMID: 26106858 Free PMC article.
Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer.
Yang S, Che SP, Kurywchak P, Tavormina JL, Gansmo LB, Correa de Sampaio P, Tachezy M, Bockhorn M, Gebauer F, Haltom AR, Melo SA, LeBleu VS, Kalluri R. Yang S, et al. Among authors: kalluri r. Cancer Biol Ther. 2017 Mar 4;18(3):158-165. doi: 10.1080/15384047.2017.1281499. Epub 2017 Jan 25. Cancer Biol Ther. 2017. PMID: 28121262 Free PMC article.
384 results