Kalinowski DS - Search Results

1

Novel Mechanism of Cytotoxicity for the Selective Selenosemicarbazone, 2-Acetylpyridine 4,4-Dimethyl-3-selenosemicarbazone (Ap44mSe): Lysosomal Membrane Permeabilization.

Al-Eisawi Z, Stefani C, Jansson PJ, Arvind A, Sharpe PC, Basha MT, Iskander GM, Kumar N, Kovacevic Z, Lane DJ, Sahni S, Bernhardt PV, Richardson DR, Kalinowski DS. Al-Eisawi Z, et al. Among authors: kalinowski ds. J Med Chem. 2016 Jan 14;59(1):294-312. doi: 10.1021/acs.jmedchem.5b01399. Epub 2015 Dec 31. J Med Chem. 2016. PMID: 26645570

2

Dipyridyl thiosemicarbazone chelators with potent and selective antitumor activity form iron complexes with redox activity.

Richardson DR, Sharpe PC, Lovejoy DB, Senaratne D, Kalinowski DS, Islam M, Bernhardt PV. Richardson DR, et al. Among authors: kalinowski ds. J Med Chem. 2006 Nov 2;49(22):6510-21. doi: 10.1021/jm0606342. J Med Chem. 2006. PMID: 17064069

3

Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.

Kalinowski DS, Yu Y, Sharpe PC, Islam M, Liao YT, Lovejoy DB, Kumar N, Bernhardt PV, Richardson DR. Kalinowski DS, et al. J Med Chem. 2007 Jul 26;50(15):3716-29. doi: 10.1021/jm070445z. Epub 2007 Jun 30. J Med Chem. 2007. PMID: 17602603

4

Tuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligands.

Bernhardt PV, Wilson GJ, Sharpe PC, Kalinowski DS, Richardson DR. Bernhardt PV, et al. Among authors: kalinowski ds. J Biol Inorg Chem. 2008 Jan;13(1):107-19. doi: 10.1007/s00775-007-0300-4. Epub 2007 Sep 25. J Biol Inorg Chem. 2008. PMID: 17899222

5

Design, synthesis, and characterization of new iron chelators with anti-proliferative activity: structure-activity relationships of novel thiohydrazone analogues.

Kalinowski DS, Sharpe PC, Bernhardt PV, Richardson DR. Kalinowski DS, et al. J Med Chem. 2007 Nov 29;50(24):6212-25. doi: 10.1021/jm070839q. Epub 2007 Oct 27. J Med Chem. 2007. PMID: 17963372

6

Structure-activity relationships of novel iron chelators for the treatment of iron overload disease: the methyl pyrazinylketone isonicotinoyl hydrazone series.

Kalinowski DS, Sharpe PC, Bernhardt PV, Richardson DR. Kalinowski DS, et al. J Med Chem. 2008 Jan 24;51(2):331-44. doi: 10.1021/jm7012562. Epub 2007 Dec 27. J Med Chem. 2008. PMID: 18159922

7

Iron chelators of the dipyridylketone thiosemicarbazone class: precomplexation and transmetalation effects on anticancer activity.

Bernhardt PV, Sharpe PC, Islam M, Lovejoy DB, Kalinowski DS, Richardson DR. Bernhardt PV, et al. Among authors: kalinowski ds. J Med Chem. 2009 Jan 22;52(2):407-15. doi: 10.1021/jm801012z. J Med Chem. 2009. PMID: 19090766

8

2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: redox activity, iron complexation and characterization of their antitumor activity.

Richardson DR, Kalinowski DS, Richardson V, Sharpe PC, Lovejoy DB, Islam M, Bernhardt PV. Richardson DR, et al. Among authors: kalinowski ds. J Med Chem. 2009 Mar 12;52(5):1459-70. doi: 10.1021/jm801585u. J Med Chem. 2009. PMID: 19216562

9

Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors.

Yu Y, Kalinowski DS, Kovacevic Z, Siafakas AR, Jansson PJ, Stefani C, Lovejoy DB, Sharpe PC, Bernhardt PV, Richardson DR. Yu Y, et al. Among authors: kalinowski ds. J Med Chem. 2009 Sep 10;52(17):5271-94. doi: 10.1021/jm900552r. J Med Chem. 2009. PMID: 19601577 Review. No abstract available.

10

Synthetic and natural products as iron chelators.

Sharpe PC, Richardson DR, Kalinowski DS, Bernhardt PV. Sharpe PC, et al. Among authors: kalinowski ds. Curr Top Med Chem. 2011;11(5):591-607. doi: 10.2174/156802611794785163. Curr Top Med Chem. 2011. PMID: 21189130 Review.

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