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A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans.
Dutzan N, Kajikawa T, Abusleme L, Greenwell-Wild T, Zuazo CE, Ikeuchi T, Brenchley L, Abe T, Hurabielle C, Martin D, Morell RJ, Freeman AF, Lazarevic V, Trinchieri G, Diaz PI, Holland SM, Belkaid Y, Hajishengallis G, Moutsopoulos NM. Dutzan N, et al. Among authors: kajikawa t. Sci Transl Med. 2018 Oct 17;10(463):eaat0797. doi: 10.1126/scitranslmed.aat0797. Sci Transl Med. 2018. PMID: 30333238 Free PMC article. Clinical Trial.
Inhibition of pre-existing natural periodontitis in non-human primates by a locally administered peptide inhibitor of complement C3.
Maekawa T, Briones RA, Resuello RR, Tuplano JV, Hajishengallis E, Kajikawa T, Koutsogiannaki S, Garcia CA, Ricklin D, Lambris JD, Hajishengallis G. Maekawa T, et al. Among authors: kajikawa t. J Clin Periodontol. 2016 Mar;43(3):238-49. doi: 10.1111/jcpe.12507. Epub 2016 Mar 3. J Clin Periodontol. 2016. PMID: 26728318 Free PMC article.
Milk fat globule epidermal growth factor 8 inhibits periodontitis in non-human primates and its gingival crevicular fluid levels can differentiate periodontal health from disease in humans.
Kajikawa T, Meshikhes F, Maekawa T, Hajishengallis E, Hosur KB, Abe T, Moss K, Chavakis T, Hajishengallis G. Kajikawa T, et al. J Clin Periodontol. 2017 May;44(5):472-483. doi: 10.1111/jcpe.12707. Epub 2017 Apr 12. J Clin Periodontol. 2017. PMID: 28207941 Free PMC article.
DEL-1 promotes macrophage efferocytosis and clearance of inflammation.
Kourtzelis I, Li X, Mitroulis I, Grosser D, Kajikawa T, Wang B, Grzybek M, von Renesse J, Czogalla A, Troullinaki M, Ferreira A, Doreth C, Ruppova K, Chen LS, Hosur K, Lim JH, Chung KJ, Grossklaus S, Tausche AK, Joosten LAB, Moutsopoulos NM, Wielockx B, Castrillo A, Korostoff JM, Coskun Ü, Hajishengallis G, Chavakis T. Kourtzelis I, et al. Among authors: kajikawa t. Nat Immunol. 2019 Jan;20(1):40-49. doi: 10.1038/s41590-018-0249-1. Epub 2018 Nov 19. Nat Immunol. 2019. PMID: 30455459 Free PMC article.
Complement-Dependent Mechanisms and Interventions in Periodontal Disease.
Hajishengallis G, Kajikawa T, Hajishengallis E, Maekawa T, Reis ES, Mastellos DC, Yancopoulou D, Hasturk H, Lambris JD. Hajishengallis G, et al. Among authors: kajikawa t. Front Immunol. 2019 Mar 12;10:406. doi: 10.3389/fimmu.2019.00406. eCollection 2019. Front Immunol. 2019. PMID: 30915073 Free PMC article. Review.
Pressure Cycling Technology Assisted Mass Spectrometric Quantification of Gingival Tissue Reveals Proteome Dynamics during the Initiation and Progression of Inflammatory Periodontal Disease.
Bao K, Li X, Kajikawa T, Toshiharu A, Selevsek N, Grossmann J, Hajishengallis G, Bostanci N. Bao K, et al. Among authors: kajikawa t. Proteomics. 2020 Feb;20(3-4):e1900253. doi: 10.1002/pmic.201900253. Epub 2020 Jan 15. Proteomics. 2020. PMID: 31881116 Free PMC article.
143 results