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Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation.
Merino B, Casanueva-Álvarez E, Quesada I, González-Casimiro CM, Fernández-Díaz CM, Postigo-Casado T, Leissring MA, Kaestner KH, Perdomo G, Cózar-Castellano I. Merino B, et al. Among authors: kaestner kh. Diabetologia. 2022 Aug;65(8):1375-1389. doi: 10.1007/s00125-022-05729-y. Epub 2022 Jun 2. Diabetologia. 2022. PMID: 35652923 Free PMC article.
Transcriptomes of the major human pancreatic cell types.
Dorrell C, Schug J, Lin CF, Canaday PS, Fox AJ, Smirnova O, Bonnah R, Streeter PR, Stoeckert CJ Jr, Kaestner KH, Grompe M. Dorrell C, et al. Among authors: kaestner kh. Diabetologia. 2011 Nov;54(11):2832-44. doi: 10.1007/s00125-011-2283-5. Epub 2011 Sep 1. Diabetologia. 2011. PMID: 21882062 Free PMC article.
Epigenomic plasticity enables human pancreatic α to β cell reprogramming.
Bramswig NC, Everett LJ, Schug J, Dorrell C, Liu C, Luo Y, Streeter PR, Naji A, Grompe M, Kaestner KH. Bramswig NC, et al. Among authors: kaestner kh. J Clin Invest. 2013 Mar;123(3):1275-84. doi: 10.1172/JCI66514. Epub 2013 Feb 22. J Clin Invest. 2013. PMID: 23434589 Free PMC article.
Transcriptional and epigenetic regulation in human islets.
Bramswig NC, Kaestner KH. Bramswig NC, et al. Among authors: kaestner kh. Diabetologia. 2014 Mar;57(3):451-4. doi: 10.1007/s00125-013-3150-3. Epub 2013 Dec 21. Diabetologia. 2014. PMID: 24362728 Free PMC article. Review.
Organisation of the human pancreas in health and in diabetes.
Atkinson MA, Campbell-Thompson M, Kusmartseva I, Kaestner KH. Atkinson MA, et al. Among authors: kaestner kh. Diabetologia. 2020 Oct;63(10):1966-1973. doi: 10.1007/s00125-020-05203-7. Epub 2020 Sep 7. Diabetologia. 2020. PMID: 32894306 Free PMC article. Review.
413 results