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Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life.
Uhlmann RE, Rother C, Rasmussen J, Schelle J, Bergmann C, Ullrich Gavilanes EM, Fritschi SK, Buehler A, Baumann F, Skodras A, Al-Shaana R, Beschorner N, Ye L, Kaeser SA, Obermüller U, Christensen S, Kartberg F, Stavenhagen JB, Rahfeld JU, Cynis H, Qian F, Weinreb PH, Bussiere T, Walker LC, Staufenbiel M, Jucker M. Uhlmann RE, et al. Among authors: kaeser sa. Nat Neurosci. 2020 Dec;23(12):1580-1588. doi: 10.1038/s41593-020-00737-w. Epub 2020 Nov 16. Nat Neurosci. 2020. PMID: 33199898 Free PMC article.
Extracellular amyloid formation and associated pathology in neural grafts.
Meyer-Luehmann M, Stalder M, Herzig MC, Kaeser SA, Kohler E, Pfeifer M, Boncristiano S, Mathews PM, Mercken M, Abramowski D, Staufenbiel M, Jucker M. Meyer-Luehmann M, et al. Among authors: kaeser sa. Nat Neurosci. 2003 Apr;6(4):370-7. doi: 10.1038/nn1022. Nat Neurosci. 2003. PMID: 12598899
Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology.
Radde R, Bolmont T, Kaeser SA, Coomaraswamy J, Lindau D, Stoltze L, Calhoun ME, Jäggi F, Wolburg H, Gengler S, Haass C, Ghetti B, Czech C, Hölscher C, Mathews PM, Jucker M. Radde R, et al. Among authors: kaeser sa. EMBO Rep. 2006 Sep;7(9):940-6. doi: 10.1038/sj.embor.7400784. Epub 2006 Aug 11. EMBO Rep. 2006. PMID: 16906128 Free PMC article.
Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host.
Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AL, Vigouret JM, Paganetti P, Walsh DM, Mathews PM, Ghiso J, Staufenbiel M, Walker LC, Jucker M. Meyer-Luehmann M, et al. Science. 2006 Sep 22;313(5794):1781-4. doi: 10.1126/science.1131864. Science. 2006. PMID: 16990547
Cystatin C modulates cerebral beta-amyloidosis.
Kaeser SA, Herzig MC, Coomaraswamy J, Kilger E, Selenica ML, Winkler DT, Staufenbiel M, Levy E, Grubb A, Jucker M. Kaeser SA, et al. Nat Genet. 2007 Dec;39(12):1437-9. doi: 10.1038/ng.2007.23. Epub 2007 Nov 18. Nat Genet. 2007. PMID: 18026102
Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease.
Coomaraswamy J, Kilger E, Wölfing H, Schäfer C, Kaeser SA, Wegenast-Braun BM, Hefendehl JK, Wolburg H, Mazzella M, Ghiso J, Goedert M, Akiyama H, Garcia-Sierra F, Wolfer DP, Mathews PM, Jucker M. Coomaraswamy J, et al. Among authors: kaeser sa. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7969-74. doi: 10.1073/pnas.1001056107. Epub 2010 Apr 12. Proc Natl Acad Sci U S A. 2010. PMID: 20385796 Free PMC article.
Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis.
Eisele YS, Obermüller U, Heilbronner G, Baumann F, Kaeser SA, Wolburg H, Walker LC, Staufenbiel M, Heikenwalder M, Jucker M. Eisele YS, et al. Among authors: kaeser sa. Science. 2010 Nov 12;330(6006):980-2. doi: 10.1126/science.1194516. Epub 2010 Oct 21. Science. 2010. PMID: 20966215 Free PMC article.
35 results