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Year Number of Results
2004 2
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2007 3
2012 1
2013 3
2014 5
2015 5
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2017 7
2018 4
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2020 3
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47 results

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Page 1
Structure-Interaction Relationship of Polymyxins with Lung Surfactant.
Jiang X, Patil NA, Xu Y, Wickremasinghe H, Zhou QT, Zhou F, Thompson PE, Wang L, Xiao M, Roberts KD, Velkov T, Li J. Jiang X, et al. Among authors: roberts kd. J Med Chem. 2023 Dec 14;66(23):16109-16119. doi: 10.1021/acs.jmedchem.3c01497. Epub 2023 Nov 29. J Med Chem. 2023. PMID: 38019899
Critical Role of Position 10 Residue in the Polymyxin Antimicrobial Activity.
Patil NA, Ma W, Jiang X, He X, Yu HH, Wickremasinghe H, Wang J, Thompson PE, Velkov T, Roberts KD, Li J. Patil NA, et al. Among authors: roberts kd. J Med Chem. 2023 Feb 23;66(4):2865-2876. doi: 10.1021/acs.jmedchem.2c01915. Epub 2023 Feb 6. J Med Chem. 2023. PMID: 36745479
A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens.
Roberts KD, Zhu Y, Azad MAK, Han ML, Wang J, Wang L, Yu HH, Horne AS, Pinson JA, Rudd D, Voelcker NH, Patil NA, Zhao J, Jiang X, Lu J, Chen K, Lomovskaya O, Hecker SJ, Thompson PE, Nation RL, Dudley MN, Griffith DC, Velkov T, Li J. Roberts KD, et al. Nat Commun. 2022 Mar 25;13(1):1625. doi: 10.1038/s41467-022-29234-3. Nat Commun. 2022. PMID: 35338128 Free PMC article.
A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threatening Acinetobacter baumannii.
Jiang X, Patil NA, Azad MAK, Wickremasinghe H, Yu H, Zhao J, Zhang X, Li M, Gong B, Wan L, Ma W, Thompson PE, Yang K, Yuan B, Schreiber F, Wang L, Velkov T, Roberts KD, Li J. Jiang X, et al. Among authors: roberts kd. Chem Sci. 2021 Aug 19;12(36):12211-12220. doi: 10.1039/d1sc03460j. eCollection 2021 Sep 22. Chem Sci. 2021. PMID: 34667587 Free PMC article.
Synchrotron-based X-ray fluorescence microscopy reveals accumulation of polymyxins in single human alveolar epithelial cells.
Azad MAK, Zhang S, Li J, Kim Y, Yu HH, Fulcher AJ, Howard DL, de Jonge MD, James SA, Roberts KD, Velkov T, Fu J, Zhou QT, Li J. Azad MAK, et al. Among authors: roberts kd. Antimicrob Agents Chemother. 2023 May 1;65(5):e02314-20. doi: 10.1128/AAC.02314-20. Epub 2021 Mar 1. Antimicrob Agents Chemother. 2023. PMID: 33649114 Free PMC article.
Molecular dynamics simulations informed by membrane lipidomics reveal the structure-interaction relationship of polymyxins with the lipid A-based outer membrane of Acinetobacter baumannii.
Jiang X, Yang K, Yuan B, Han M, Zhu Y, Roberts KD, Patil NA, Li J, Gong B, Hancock REW, Velkov T, Schreiber F, Wang L, Li J. Jiang X, et al. Among authors: roberts kd. J Antimicrob Chemother. 2020 Dec 1;75(12):3534-3543. doi: 10.1093/jac/dkaa376. J Antimicrob Chemother. 2020. PMID: 32911540 Free PMC article.
47 results