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Page 1
Macrophages acquire a TNF-dependent inflammatory memory in allergic asthma.
Lechner A, Henkel FDR, Hartung F, Bohnacker S, Alessandrini F, Gubernatorova EO, Drutskaya MS, Angioni C, Schreiber Y, Haimerl P, Ge Y, Thomas D, Kabat AM, Pearce EJ, Ohnmacht C, Nedospasov SA, Murray PJ, Chaker AM, Schmidt-Weber CB, Esser-von Bieren J. Lechner A, et al. Among authors: kabat am. J Allergy Clin Immunol. 2022 Jun;149(6):2078-2090. doi: 10.1016/j.jaci.2021.11.026. Epub 2021 Dec 30. J Allergy Clin Immunol. 2022. PMID: 34974067 Free article.
Inflammation by way of macrophage metabolism.
Kabat AM, Pearce EJ. Kabat AM, et al. Science. 2017 May 5;356(6337):488-489. doi: 10.1126/science.aan2691. Science. 2017. PMID: 28473549 No abstract available.
Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2.
Sanin DE, Matsushita M, Klein Geltink RI, Grzes KM, van Teijlingen Bakker N, Corrado M, Kabat AM, Buck MD, Qiu J, Lawless SJ, Cameron AM, Villa M, Baixauli F, Patterson AE, Hässler F, Curtis JD, O'Neill CM, O'Sullivan D, Wu D, Mittler G, Huang SC, Pearce EL, Pearce EJ. Sanin DE, et al. Among authors: kabat am. Immunity. 2018 Dec 18;49(6):1021-1033.e6. doi: 10.1016/j.immuni.2018.10.011. Immunity. 2018. PMID: 30566880 Free PMC article.
Metabolic conditioning of CD8+ effector T cells for adoptive cell therapy.
Klein Geltink RI, Edwards-Hicks J, Apostolova P, O'Sullivan D, Sanin DE, Patterson AE, Puleston DJ, Ligthart NAM, Buescher JM, Grzes KM, Kabat AM, Stanczak M, Curtis JD, Hässler F, Uhl FM, Fabri M, Zeiser R, Pearce EJ, Pearce EL. Klein Geltink RI, et al. Among authors: kabat am. Nat Metab. 2020 Aug;2(8):703-716. doi: 10.1038/s42255-020-0256-z. Epub 2020 Aug 3. Nat Metab. 2020. PMID: 32747793 Free PMC article.
IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection.
Montes de Oca M, de Labastida Rivera F, Winterford C, Frame TCM, Ng SS, Amante FH, Edwards CL, Bukali L, Wang Y, Uzonna JE, Kuns RD, Zhang P, Kabat A, Klein Geltink RI, Pearce EJ, Hill GR, Engwerda CR. Montes de Oca M, et al. PLoS Pathog. 2020 Oct 13;16(10):e1008994. doi: 10.1371/journal.ppat.1008994. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33049000 Free PMC article.
Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH.
Dudek M, Pfister D, Donakonda S, Filpe P, Schneider A, Laschinger M, Hartmann D, Hüser N, Meiser P, Bayerl F, Inverso D, Wigger J, Sebode M, Öllinger R, Rad R, Hegenbarth S, Anton M, Guillot A, Bowman A, Heide D, Müller F, Ramadori P, Leone V, Garcia-Caceres C, Gruber T, Seifert G, Kabat AM, Mallm JP, Reider S, Effenberger M, Roth S, Billeter AT, Müller-Stich B, Pearce EJ, Koch-Nolte F, Käser R, Tilg H, Thimme R, Boettler T, Tacke F, Dufour JF, Haller D, Murray PJ, Heeren R, Zehn D, Böttcher JP, Heikenwälder M, Knolle PA. Dudek M, et al. Among authors: kabat am. Nature. 2021 Apr;592(7854):444-449. doi: 10.1038/s41586-021-03233-8. Epub 2021 Mar 24. Nature. 2021. PMID: 33762736
Author Correction: Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH.
Dudek M, Pfister D, Donakonda S, Filpe P, Schneider A, Laschinger M, Hartmann D, Hüser N, Meiser P, Bayerl F, Inverso D, Wigger J, Sebode M, Öllinger R, Rad R, Hegenbarth S, Anton M, Guillot A, Bowman A, Heide D, Müller F, Ramadori P, Leone V, Garcia-Caceres C, Gruber T, Seifert G, Kabat AM, Mallm JP, Reider S, Effenberger M, Roth S, Billeter AT, Müller-Stich B, Pearce EJ, Koch-Nolte F, Käser R, Tilg H, Thimme R, Boettler T, Tacke F, Dufour JF, Haller D, Murray PJ, Heeren R, Zehn D, Böttcher JP, Heikenwälder M, Knolle PA. Dudek M, et al. Among authors: kabat am. Nature. 2021 May;593(7860):E14. doi: 10.1038/s41586-021-03568-2. Nature. 2021. PMID: 33972788 No abstract available.
Fever supports CD8+ effector T cell responses by promoting mitochondrial translation.
O'Sullivan D, Stanczak MA, Villa M, Uhl FM, Corrado M, Klein Geltink RI, Sanin DE, Apostolova P, Rana N, Edwards-Hicks J, Grzes KM, Kabat AM, Kyle RL, Fabri M, Curtis JD, Buck MD, Patterson AE, Regina A, Field CS, Baixauli F, Puleston DJ, Pearce EJ, Zeiser R, Pearce EL. O'Sullivan D, et al. Among authors: kabat am. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2023752118. doi: 10.1073/pnas.2023752118. Epub 2021 Jun 14. Proc Natl Acad Sci U S A. 2021. PMID: 34161266 Free PMC article.
Plasmacytoid dendritic cell activation is dependent on coordinated expression of distinct amino acid transporters.
Grzes KM, Sanin DE, Kabat AM, Stanczak MA, Edwards-Hicks J, Matsushita M, Hackl A, Hässler F, Knoke K, Zahalka S, Villa M, Kofler DM, Voll RE, Zigrino P, Fabri M, Pearce EL, Pearce EJ. Grzes KM, et al. Among authors: kabat am. Immunity. 2021 Nov 9;54(11):2514-2530.e7. doi: 10.1016/j.immuni.2021.10.009. Epub 2021 Oct 29. Immunity. 2021. PMID: 34717796 Free article.
Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF.
Dichtl S, Sanin DE, Koss CK, Willenborg S, Petzold A, Tanzer MC, Dahl A, Kabat AM, Lindenthal L, Zeitler L, Satzinger S, Strasser A, Mann M, Roers A, Eming SA, El Kasmi KC, Pearce EJ, Murray PJ. Dichtl S, et al. Among authors: kabat am. Life Sci Alliance. 2022 Jan 13;5(4):e202101315. doi: 10.26508/lsa.202101315. Print 2022 Apr. Life Sci Alliance. 2022. PMID: 35027468 Free PMC article.
28 results