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Page 1
Metabolic Origins of Heart Failure.
Wende AR, Brahma MK, McGinnis GR, Young ME. Wende AR, et al. JACC Basic Transl Sci. 2017 Jun;2(3):297-310. doi: 10.1016/j.jacbts.2016.11.009. JACC Basic Transl Sci. 2017. PMID: 28944310 Free PMC article.
Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.
Wende AR, O'Neill BT, Bugger H, Riehle C, Tuinei J, Buchanan J, Tsushima K, Wang L, Caro P, Guo A, Sloan C, Kim BJ, Wang X, Pereira RO, McCrory MA, Nye BG, Benavides GA, Darley-Usmar VM, Shioi T, Weimer BC, Abel ED. Wende AR, et al. Mol Cell Biol. 2015 Mar;35(5):831-46. doi: 10.1128/MCB.01109-14. Epub 2014 Dec 22. Mol Cell Biol. 2015. PMID: 25535334 Free PMC article.
Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.
Riehle C, Wende AR, Zhu Y, Oliveira KJ, Pereira RO, Jaishy BP, Bevins J, Valdez S, Noh J, Kim BJ, Moreira AB, Weatherford ET, Manivel R, Rawlings TA, Rech M, White MF, Abel ED. Riehle C, et al. Mol Cell Biol. 2014 Sep 15;34(18):3450-60. doi: 10.1128/MCB.00426-14. Epub 2014 Jul 7. Mol Cell Biol. 2014. PMID: 25002528 Free PMC article.
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
Riehle C, Wende AR, Sena S, Pires KM, Pereira RO, Zhu Y, Bugger H, Frank D, Bevins J, Chen D, Perry CN, Dong XC, Valdez S, Rech M, Sheng X, Weimer BC, Gottlieb RA, White MF, Abel ED. Riehle C, et al. J Clin Invest. 2013 Dec;123(12):5319-33. doi: 10.1172/JCI71171. Epub 2013 Nov 1. J Clin Invest. 2013. PMID: 24177427 Free PMC article.
APpEaLINg therapeutic target for obesity cardiomyopathy?
Wende AR, Young ME. Wende AR, et al. J Mol Cell Cardiol. 2013 Oct;63:165-8. doi: 10.1016/j.yjmcc.2013.08.001. Epub 2013 Aug 12. J Mol Cell Cardiol. 2013. PMID: 23948484 Free PMC article. No abstract available.