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Comprehensive Integration of Multiple Single-Cell Transcriptomic Data Sets Defines Distinct Cell Populations and Their Phenotypic Changes in Murine Atherosclerosis.
Sharma D, Worssam MD, Pedroza AJ, Dalal AR, Alemany H, Kim HJ, Kundu R, Fischbein MP, Cheng P, Wirka R, Quertermous T. Sharma D, et al. Arterioscler Thromb Vasc Biol. 2024 Feb;44(2):391-408. doi: 10.1161/ATVBAHA.123.320030. Epub 2023 Dec 28. Arterioscler Thromb Vasc Biol. 2024. PMID: 38152886
Embryologic Origin Influences Smooth Muscle Cell Phenotypic Modulation Signatures in Murine Marfan Syndrome Aortic Aneurysm.
Pedroza AJ, Dalal AR, Shad R, Yokoyama N, Nakamura K, Cheng P, Wirka RC, Mitchel O, Baiocchi M, Hiesinger W, Quertermous T, Fischbein MP. Pedroza AJ, et al. Arterioscler Thromb Vasc Biol. 2022 Sep;42(9):1154-1168. doi: 10.1161/ATVBAHA.122.317381. Epub 2022 Jul 7. Arterioscler Thromb Vasc Biol. 2022. PMID: 35861960 Free PMC article.
ZEB2 Shapes the Epigenetic Landscape of Atherosclerosis.
Cheng P, Wirka RC, Shoa Clarke L, Zhao Q, Kundu R, Nguyen T, Nair S, Sharma D, Kim HJ, Shi H, Assimes T, Brian Kim J, Kundaje A, Quertermous T. Cheng P, et al. Circulation. 2022 Feb 8;145(6):469-485. doi: 10.1161/CIRCULATIONAHA.121.057789. Epub 2022 Jan 6. Circulation. 2022. PMID: 34990206 Free PMC article.
Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm.
Pedroza AJ, Tashima Y, Shad R, Cheng P, Wirka R, Churovich S, Nakamura K, Yokoyama N, Cui JZ, Iosef C, Hiesinger W, Quertermous T, Fischbein MP. Pedroza AJ, et al. Arterioscler Thromb Vasc Biol. 2020 Sep;40(9):2195-2211. doi: 10.1161/ATVBAHA.120.314670. Epub 2020 Jul 23. Arterioscler Thromb Vasc Biol. 2020. PMID: 32698686 Free PMC article.
Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases.
Nurnberg ST, Guerraty MA, Wirka RC, Rao HS, Pjanic M, Norton S, Serrano F, Perisic L, Elwyn S, Pluta J, Zhao W, Testa S, Park Y, Nguyen T, Ko YA, Wang T, Hedin U, Sinha S, Barash Y, Brown CD, Quertermous T, Rader DJ. Nurnberg ST, et al. PLoS Genet. 2020 Jan 9;16(1):e1008538. doi: 10.1371/journal.pgen.1008538. eCollection 2020 Jan. PLoS Genet. 2020. PMID: 31917787 Free PMC article.