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Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase.
Pein H, Ville A, Pace S, Temml V, Garscha U, Raasch M, Alsabil K, Viault G, Dinh CP, Guilet D, Troisi F, Neukirch K, König S, Bilancia R, Waltenberger B, Stuppner H, Wallert M, Lorkowski S, Weinigel C, Rummler S, Birringer M, Roviezzo F, Sautebin L, Helesbeux JJ, Séraphin D, Mosig AS, Schuster D, Rossi A, Richomme P, Werz O, Koeberle A. Pein H, et al. Among authors: konig s. Nat Commun. 2018 Sep 20;9(1):3834. doi: 10.1038/s41467-018-06158-5. Nat Commun. 2018. PMID: 30237488 Free PMC article.
Myxochelins target human 5-lipoxygenase.
Schieferdecker S, König S, Koeberle A, Dahse HM, Werz O, Nett M. Schieferdecker S, et al. Among authors: konig s. J Nat Prod. 2015 Feb 27;78(2):335-8. doi: 10.1021/np500909b. Epub 2015 Feb 16. J Nat Prod. 2015. PMID: 25686392
Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase.
Garscha U, Romp E, Pace S, Rossi A, Temml V, Schuster D, König S, Gerstmeier J, Liening S, Werner M, Atze H, Wittmann S, Weinigel C, Rummler S, Scriba GK, Sautebin L, Werz O. Garscha U, et al. Among authors: konig s. Sci Rep. 2017 Aug 24;7(1):9398. doi: 10.1038/s41598-017-09795-w. Sci Rep. 2017. PMID: 28839250 Free PMC article.
990 results