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Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity.
de Jong SE, van Unen V, Manurung MD, Stam KA, Goeman JJ, Jochems SP, Höllt T, Pezzotti N, Mouwenda YD, Betouke Ongwe ME, Lorenz FR, Kruize YCM, Azimi S, König MH, Vilanova A, Eisemann E, Lelieveldt BPF, Roestenberg M, Sim BKL, Reinders MJT, Fendel R, Hoffman SL, Kremsner PG, Koning F, Mordmüller B, Lell B, Yazdanbakhsh M. de Jong SE, et al. Among authors: konig mh. Nat Immunol. 2021 May;22(5):654-665. doi: 10.1038/s41590-021-00911-7. Epub 2021 Apr 22. Nat Immunol. 2021. PMID: 33888898 Clinical Trial.
Helminth infections drive heterogeneity in human type 2 and regulatory cells.
de Ruiter K, Jochems SP, Tahapary DL, Stam KA, König M, van Unen V, Laban S, Höllt T, Mbow M, Lelieveldt BPF, Koning F, Sartono E, Smit JWA, Supali T, Yazdanbakhsh M. de Ruiter K, et al. Sci Transl Med. 2020 Jan 1;12(524):eaaw3703. doi: 10.1126/scitranslmed.aaw3703. Sci Transl Med. 2020. PMID: 31894102 Clinical Trial.
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19.
Roukens AHE, Pothast CR, König M, Huisman W, Dalebout T, Tak T, Azimi S, Kruize Y, Hagedoorn RS, Zlei M, Staal FJT, de Bie FJ, van Dongen JJM, Arbous SM, Zhang JLH, Verheij M, Prins C, van der Does AM, Hiemstra PS, de Vries JJC, Janse JJ, Roestenberg M, Myeni SK, Kikkert M, Yazdanbakhsh M, Heemskerk MHM, Smits HH, Jochems SP; in collaboration with BEAT-COVID group; in collaboration with COVID-19 LUMC group. Roukens AHE, et al. Nat Immunol. 2022 Jan;23(1):23-32. doi: 10.1038/s41590-021-01095-w. Epub 2021 Dec 22. Nat Immunol. 2022. PMID: 34937933