Displacement of rhodopsin by GDP from three-loop interaction with transducin depends critically on the diphosphate beta-position.
Kahlert M, König B, Hofmann KP.
Kahlert M, et al. Among authors: konig b.
J Biol Chem. 1990 Nov 5;265(31):18928-32.
J Biol Chem. 1990.
PMID: 2229054
Free article.
We discuss a generalized induced fit mechanism, where MII induces opening of the Gt nucleotide site and release of GDP which in turn is obligatory to establish the MII-stabilizing rhodopsin-Gt three-loop interaction (Konig, B., Arendt, A., McDowell, J.H., Kahlert, M …
We discuss a generalized induced fit mechanism, where MII induces opening of the Gt nucleotide site and release of GDP which in turn is obli …