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The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease.
Rantamäki T, Kemppainen S, Autio H, Stavén S, Koivisto H, Kojima M, Antila H, Miettinen PO, Kärkkäinen E, Karpova N, Vesa L, Lindemann L, Hoener MC, Tanila H, Castrén E. Rantamäki T, et al. Among authors: karkkainen e. PLoS One. 2013 Jul 3;8(7):e68722. doi: 10.1371/journal.pone.0068722. Print 2013. PLoS One. 2013. PMID: 23844236 Free PMC article.
Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice.
Kemppainen S, Rantamäki T, Jerónimo-Santos A, Lavasseur G, Autio H, Karpova N, Kärkkäinen E, Stavén S, Vicente Miranda H, Outeiro TF, Diógenes MJ, Laroche S, Davis S, Sebastião AM, Castrén E, Tanila H. Kemppainen S, et al. Among authors: karkkainen e. Neurobiol Aging. 2012 Jun;33(6):1122.e23-39. doi: 10.1016/j.neurobiolaging.2011.11.006. Epub 2011 Dec 30. Neurobiol Aging. 2012. PMID: 22209410
The calcium-activated chloride channel-associated protein rCLCA2 is expressed throughout rat epidermis, facilitates apoptosis and is downmodulated by UVB.
Hämäläinen L, Bart G, Takabe P, Rauhala L, Deen A, Pasonen-Seppänen S, Kärkkäinen E, Kärnä R, Kumlin T, Tammi MI, Tammi RH. Hämäläinen L, et al. Among authors: karkkainen e. Histochem Cell Biol. 2021 May;155(5):605-615. doi: 10.1007/s00418-021-01962-5. Epub 2021 Jan 23. Histochem Cell Biol. 2021. PMID: 33486586 Free PMC article.
Proof of Concept for Cell Culture-Based Coffee.
Aisala H, Kärkkäinen E, Jokinen I, Seppänen-Laakso T, Rischer H. Aisala H, et al. Among authors: karkkainen e. J Agric Food Chem. 2023 Nov 29;71(47):18478-18488. doi: 10.1021/acs.jafc.3c04503. Epub 2023 Nov 16. J Agric Food Chem. 2023. PMID: 37972222 Free PMC article.
Fluorescent optotracers for bacterial and biofilm detection and diagnostics.
Richter-Dahlfors A, Kärkkäinen E, Choong FX. Richter-Dahlfors A, et al. Among authors: karkkainen e. Sci Technol Adv Mater. 2023 Sep 5;24(1):2246867. doi: 10.1080/14686996.2023.2246867. eCollection 2023. Sci Technol Adv Mater. 2023. PMID: 37680974 Free PMC article. Review.
Tumor-independent Detection of Inherited Mismatch Repair Deficiency for the Diagnosis of Lynch Syndrome with High Specificity and Sensitivity.
Kansikas M, Vähätalo L, Kantelinen J, Kasela M, Putula J, Døhlen A, Paloviita P, Kärkkäinen E, Lahti N, Arnez P, Kilpinen S, Alcala-Repo B, Pylvänäinen K, Pöyhönen M, Peltomäki P, Järvinen HJ, Seppälä TT, Renkonen-Sinisalo L, Lepistö A, Mecklin JP, Nyström M. Kansikas M, et al. Among authors: karkkainen e. Cancer Res Commun. 2023 Mar 2;3(3):361-370. doi: 10.1158/2767-9764.CRC-22-0384. eCollection 2023 Mar. Cancer Res Commun. 2023. PMID: 36875157 Free PMC article.
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