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Preservation of microscopic fur, feather, and bast fibers in the Mesolithic ochre grave of Majoonsuo, Eastern Finland.
Kirkinen T, López-Costas O, Martínez Cortizas A, Sihvo SP, Ruhanen H, Käkelä R, Nyman JE, Mikkola E, Rantanen J, Hertell E, Ahola M, Roiha J, Mannermaa K. Kirkinen T, et al. Among authors: kakela r. PLoS One. 2022 Sep 27;17(9):e0274849. doi: 10.1371/journal.pone.0274849. eCollection 2022. PLoS One. 2022. PMID: 36166442 Free PMC article.
PNPLA3 mediates hepatocyte triacylglycerol remodeling.
Ruhanen H, Perttilä J, Hölttä-Vuori M, Zhou Y, Yki-Järvinen H, Ikonen E, Käkelä R, Olkkonen VM. Ruhanen H, et al. Among authors: kakela r. J Lipid Res. 2014 Apr;55(4):739-46. doi: 10.1194/jlr.M046607. Epub 2014 Feb 7. J Lipid Res. 2014. PMID: 24511104 Free PMC article.
Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22.
Hyvärinen K, Holopainen M, Skirdenko V, Ruhanen H, Lehenkari P, Korhonen M, Käkelä R, Laitinen S, Kerkelä E. Hyvärinen K, et al. Among authors: kakela r. Front Immunol. 2018 Apr 12;9:771. doi: 10.3389/fimmu.2018.00771. eCollection 2018. Front Immunol. 2018. PMID: 29706969 Free PMC article.
ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins.
Ruhanen H, Haridas PAN, Minicocci I, Taskinen JH, Palmas F, di Costanzo A, D'Erasmo L, Metso J, Partanen J, Dalli J, Zhou Y, Arca M, Jauhiainen M, Käkelä R, Olkkonen VM. Ruhanen H, et al. Among authors: kakela r. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jul;1865(7):158679. doi: 10.1016/j.bbalip.2020.158679. Epub 2020 Mar 6. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32151767
Coordinated control of adiposity and growth by anti-anabolic kinase ERK7.
Hasygar K, Deniz O, Liu Y, Gullmets J, Hynynen R, Ruhanen H, Kokki K, Käkelä R, Hietakangas V. Hasygar K, et al. Among authors: kakela r. EMBO Rep. 2021 Feb 3;22(2):e49602. doi: 10.15252/embr.201949602. Epub 2020 Dec 28. EMBO Rep. 2021. PMID: 33369866 Free PMC article.
Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles.
Syed S, Nissilä E, Ruhanen H, Fudo S, Gaytán MO, Sihvo SP, Lorey MB, Metso J, Öörni K, King SJ, Oommen OP, Jauhiainen M, Meri S, Käkelä R, Haapasalo K. Syed S, et al. Among authors: kakela r. iScience. 2021 May 12;24(6):102535. doi: 10.1016/j.isci.2021.102535. eCollection 2021 Jun 25. iScience. 2021. PMID: 34124613 Free PMC article.
108 results