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Page 1
Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis.
Ahangari F, Becker C, Foster DG, Chioccioli M, Nelson M, Beke K, Wang X, Justet A, Adams T, Readhead B, Meador C, Correll K, Lili LN, Roybal HM, Rose KA, Ding S, Barnthaler T, Briones N, DeIuliis G, Schupp JC, Li Q, Omote N, Aschner Y, Sharma L, Kopf KW, Magnusson B, Hicks R, Backmark A, Dela Cruz CS, Rosas I, Cousens LP, Dudley JT, Kaminski N, Downey GP. Ahangari F, et al. Among authors: justet a. Am J Respir Crit Care Med. 2022 Dec 15;206(12):1463-1479. doi: 10.1164/rccm.202010-3832OC. Am J Respir Crit Care Med. 2022. PMID: 35998281 Free PMC article.
Anti-parietal cell autoimmunity is associated with an accelerated decline of lung function in IPF patients.
Beltramo G, Thabut G, Peron N, Nicaise P, Cazes A, Debray MP, Joannes A, Castier Y, Mailleux AA, Frija J, Pradère P, Justet A, Borie R, Dombret MC, Taille C, Aubier M, Crestani B. Beltramo G, et al. Among authors: justet a. Respir Med. 2018 Feb;135:15-21. doi: 10.1016/j.rmed.2017.12.011. Epub 2018 Jan 2. Respir Med. 2018. PMID: 29414448 Free article.
Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis.
Juge PA, Borie R, Kannengiesser C, Gazal S, Revy P, Wemeau-Stervinou L, Debray MP, Ottaviani S, Marchand-Adam S, Nathan N, Thabut G, Richez C, Nunes H, Callebaut I, Justet A, Leulliot N, Bonnefond A, Salgado D, Richette P, Desvignes JP, Lioté H, Froguel P, Allanore Y, Sand O, Dromer C, Flipo RM, Clément A, Béroud C, Sibilia J, Coustet B, Cottin V, Boissier MC, Wallaert B, Schaeverbeke T, Dastot le Moal F, Frazier A, Ménard C, Soubrier M, Saidenberg N, Valeyre D, Amselem S; FREX consortium; Boileau C, Crestani B, Dieudé P. Juge PA, et al. Among authors: justet a. Eur Respir J. 2017 May 11;49(5):1602314. doi: 10.1183/13993003.02314-2016. Print 2017 May. Eur Respir J. 2017. PMID: 28495692 Free article.
Pharmacological management of IPF.
Borie R, Justet A, Beltramo G, Manali ED, Pradère P, Spagnolo P, Crestani B. Borie R, et al. Among authors: justet a. Respirology. 2016 May;21(4):615-25. doi: 10.1111/resp.12778. Epub 2016 Apr 12. Respirology. 2016. PMID: 27072575 Free article. Review.
FGF9 prevents pleural fibrosis induced by intrapleural adenovirus injection in mice.
Justet A, Joannes A, Besnard V, Marchal-Sommé J, Jaillet M, Bonniaud P, Sallenave JM, Solhonne B, Castier Y, Mordant P, Mal H, Cazes A, Borie R, Mailleux AA, Crestani B. Justet A, et al. Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L781-L795. doi: 10.1152/ajplung.00508.2016. Epub 2017 Jul 20. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28729349 Free article.
Human airway trypsin-like protease exerts potent, antifibrotic action in pulmonary fibrosis.
Menou A, Flajolet P, Duitman J, Justet A, Moog S, Jaillet M, Tabèze L, Solhonne B, Garnier M, Mal H, Mordant P, Castier Y, Cazes A, Sallenave JM, Mailleux AA, Crestani B. Menou A, et al. Among authors: justet a. FASEB J. 2018 Mar;32(3):1250-1264. doi: 10.1096/fj.201700583R. Epub 2018 Jan 3. FASEB J. 2018. PMID: 29122847
In vitro, HAT prevented specific fibrosis-associated responses in primary human pulmonary fibroblasts and induced the expression of mediators associated with the prostaglandin E2 pathway. Altogether, our findings suggested that HAT could have a protective role in IPF and o …
In vitro, HAT prevented specific fibrosis-associated responses in primary human pulmonary fibroblasts and induced the expression of mediator …
33 results