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Page 1
Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent cognitive impairment in C9orf72 BAC transgenic mice.
Jury N, Abarzua S, Diaz I, Guerra MV, Ampuero E, Cubillos P, Martinez P, Herrera-Soto A, Arredondo C, Rojas F, Manterola M, Rojas A, Montecino M, Varela-Nallar L, van Zundert B. Jury N, et al. Clin Epigenetics. 2020 Feb 18;12(1):32. doi: 10.1186/s13148-020-0816-9. Clin Epigenetics. 2020. PMID: 32070418 Free PMC article.
NMDA receptor subunit composition controls dendritogenesis of hippocampal neurons through CAMKII, CREB-P, and H3K27ac.
Bustos FJ, Jury N, Martinez P, Ampuero E, Campos M, Abarzúa S, Jaramillo K, Ibing S, Mardones MD, Haensgen H, Kzhyshkowska J, Tevy MF, Neve R, Sanhueza M, Varela-Nallar L, Montecino M, van Zundert B. Bustos FJ, et al. Among authors: jury n. J Cell Physiol. 2017 Dec;232(12):3677-3692. doi: 10.1002/jcp.25843. Epub 2017 May 11. J Cell Physiol. 2017. PMID: 28160495
Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer's disease mice.
Bustos FJ, Ampuero E, Jury N, Aguilar R, Falahi F, Toledo J, Ahumada J, Lata J, Cubillos P, Henríquez B, Guerra MV, Stehberg J, Neve RL, Inestrosa NC, Wyneken U, Fuenzalida M, Härtel S, Sena-Esteves M, Varela-Nallar L, Rots MG, Montecino M, van Zundert B. Bustos FJ, et al. Among authors: jury n. Brain. 2017 Dec 1;140(12):3252-3268. doi: 10.1093/brain/awx272. Brain. 2017. PMID: 29155979 Free PMC article.
Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain of humans and mice exposed to particulate urban air pollution.
Calderón-Garcidueñas L, Herrera-Soto A, Jury N, Maher BA, González-Maciel A, Reynoso-Robles R, Ruiz-Rudolph P, van Zundert B, Varela-Nallar L. Calderón-Garcidueñas L, et al. Among authors: jury n. Environ Res. 2020 Apr;183:109226. doi: 10.1016/j.envres.2020.109226. Epub 2020 Feb 4. Environ Res. 2020. PMID: 32045727
BET bromodomain inhibitors PFI-1 and JQ1 are identified in an epigenetic compound screen to enhance C9ORF72 gene expression and shown to ameliorate C9ORF72-associated pathological and behavioral abnormalities in a C9ALS/FTD model.
Quezada E, Cappelli C, Diaz I, Jury N, Wightman N, Brown RH Jr, Montecino M, van Zundert B. Quezada E, et al. Among authors: jury n. Clin Epigenetics. 2021 Mar 16;13(1):56. doi: 10.1186/s13148-021-01039-z. Clin Epigenetics. 2021. PMID: 33726839 Free PMC article.
Astroglial gliotransmitters released via Cx43 hemichannels regulate NMDAR-dependent transmission and short-term fear memory in the basolateral amygdala.
Linsambarth S, Carvajal FJ, Moraga-Amaro R, Mendez L, Tamburini G, Jimenez I, Verdugo DA, Gómez GI, Jury N, Martínez P, van Zundert B, Varela-Nallar L, Retamal MA, Martin C, Altenberg GA, Fiori MC, Cerpa W, Orellana JA, Stehberg J. Linsambarth S, et al. Among authors: jury n. FASEB J. 2022 Feb;36(2):e22134. doi: 10.1096/fj.202100798RR. FASEB J. 2022. PMID: 35061296
Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons.
Arredondo C, Cefaliello C, Dyrda A, Jury N, Martinez P, Díaz I, Amaro A, Tran H, Morales D, Pertusa M, Stoica L, Fritz E, Corvalán D, Abarzúa S, Méndez-Ruette M, Fernández P, Rojas F, Kumar MS, Aguilar R, Almeida S, Weiss A, Bustos FJ, González-Nilo F, Otero C, Tevy MF, Bosco DA, Sáez JC, Kähne T, Gao FB, Berry JD, Nicholson K, Sena-Esteves M, Madrid R, Varela D, Montecino M, Brown RH, van Zundert B. Arredondo C, et al. Among authors: jury n. Neuron. 2022 May 18;110(10):1656-1670.e12. doi: 10.1016/j.neuron.2022.02.010. Epub 2022 Mar 10. Neuron. 2022. PMID: 35276083 Free PMC article.
Activated endothelial cells induce a distinct type of astrocytic reactivity.
Taylor X, Cisternas P, Jury N, Martinez P, Huang X, You Y, Redding-Ochoa J, Vidal R, Zhang J, Troncoso J, Lasagna-Reeves CA. Taylor X, et al. Among authors: jury n. Commun Biol. 2022 Mar 29;5(1):282. doi: 10.1038/s42003-022-03237-8. Commun Biol. 2022. PMID: 35351973 Free PMC article.
23 results