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Inhibition of SIRT7 overcomes sorafenib acquired resistance by suppressing ERK1/2 phosphorylation via the DDX3X-mediated NLRP3 inflammasome in hepatocellular carcinoma.
Kim Y, Jung KY, Kim YH, Xu P, Kang BE, Jo Y, Pandit N, Kwon J, Gariani K, Gariani J, Lee J, Verbeek J, Nam S, Bae SJ, Ha KT, Yi HS, Shong M, Kim KH, Kim D, Jung HJ, Lee CW, Kim KR, Schoonjans K, Auwerx J, Ryu D. Kim Y, et al. Among authors: jung ky. Drug Resist Updat. 2024 Mar;73:101054. doi: 10.1016/j.drup.2024.101054. Epub 2024 Jan 17. Drug Resist Updat. 2024. PMID: 38277756 Free PMC article.
Identification of a novel SIRT7 inhibitor as anticancer drug candidate.
Kim JH, Kim D, Cho SJ, Jung KY, Kim JH, Lee JM, Jung HJ, Kim KR. Kim JH, et al. Among authors: jung ky, jung hj. Biochem Biophys Res Commun. 2019 Jan 8;508(2):451-457. doi: 10.1016/j.bbrc.2018.11.120. Epub 2018 Nov 30. Biochem Biophys Res Commun. 2019. PMID: 30503501
Synthesis and biological evaluation of thiazole derivatives as GPR119 agonists.
Kim H, Cho SJ, Yoo M, Kang SK, Kim KR, Lee HH, Song JS, Rhee SD, Jung WH, Ahn JH, Jung JK, Jung KY. Kim H, et al. Among authors: jung ky, jung wh, jung jk. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5213-5220. doi: 10.1016/j.bmcl.2017.10.046. Epub 2017 Oct 20. Bioorg Med Chem Lett. 2017. PMID: 29103971
Discovery of BET specific bromodomain inhibitors with a novel scaffold.
Pandit N, Yoo M, Hyun Park T, Kim J, Mi Kim S, Myung Lee K, Kim Y, Min Bong S, Il Lee B, Jung KY, Hoon Park C. Pandit N, et al. Among authors: jung ky. Bioorg Med Chem. 2022 Oct 15;72:116967. doi: 10.1016/j.bmc.2022.116967. Epub 2022 Aug 23. Bioorg Med Chem. 2022. PMID: 36099719
Novel brd4 inhibitors with a unique scaffold exhibit antitumor effects.
Kim YH, Kim M, Kim JE, Yoo M, Lee HK, Lee CO, Yoo M, Jung KY, Kim Y, Choi SU, Park CH. Kim YH, et al. Among authors: jung ky. Oncol Lett. 2021 Jun;21(6):473. doi: 10.3892/ol.2021.12734. Epub 2021 Apr 14. Oncol Lett. 2021. PMID: 33907583 Free PMC article.
599 results