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Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease.
Chioua M, Buzzi E, Moraleda I, Iriepa I, Maj M, Wnorowski A, Giovannini C, Tramarin A, Portali F, Ismaili L, López-Alvarado P, Bolognesi ML, Jóźwiak K, Menéndez JC, Marco-Contelles J, Bartolini M. Chioua M, et al. Among authors: jozwiak k. Eur J Med Chem. 2018 Jul 15;155:839-846. doi: 10.1016/j.ejmech.2018.06.044. Epub 2018 Jun 19. Eur J Med Chem. 2018. PMID: 29958119
Development of tricyclic N-benzyl-4-hydroxybutanamide derivatives as inhibitors of GABA transporters mGAT1-4 with anticonvulsant, antinociceptive, and antidepressant activity.
Zaręba P, Sałat K, Höfner GC, Łątka K, Bajda M, Latacz G, Kotniewicz K, Rapacz A, Podkowa A, Maj M, Jóźwiak K, Filipek B, Wanner KT, Malawska B, Kulig K. Zaręba P, et al. Among authors: jozwiak k. Eur J Med Chem. 2021 Oct 5;221:113512. doi: 10.1016/j.ejmech.2021.113512. Epub 2021 May 4. Eur J Med Chem. 2021. PMID: 34015586
Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation.
Malek R, Simakov A, Davis A, Maj M, Bernard PJ, Wnorowski A, Martin H, Marco-Contelles J, Chabchoub F, Dallemagne P, Rochais C, Jozwiak K, Ismaili L. Malek R, et al. Among authors: jozwiak k. Molecules. 2022 Dec 22;28(1):71. doi: 10.3390/molecules28010071. Molecules. 2022. PMID: 36615267 Free PMC article.
196 results