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Inhibitors of ApiAP2 protein DNA binding exhibit multistage activity against Plasmodium parasites.
Russell TJ, De Silva EK, Crowley VM, Shaw-Saliba K, Dube N, Josling G, Pasaje CFA, Kouskoumvekaki I, Panagiotou G, Niles JC, Jacobs-Lorena M, Denise Okafor C, Gamo FJ, Llinás M. Russell TJ, et al. Among authors: josling g. PLoS Pathog. 2022 Oct 12;18(10):e1010887. doi: 10.1371/journal.ppat.1010887. eCollection 2022 Oct. PLoS Pathog. 2022. PMID: 36223427 Free PMC article.
Commitment Isn't for Everyone.
Josling GA, Llinás M. Josling GA, et al. Trends Parasitol. 2019 Jun;35(6):381-383. doi: 10.1016/j.pt.2019.03.012. Epub 2019 Apr 30. Trends Parasitol. 2019. PMID: 31053335 Free PMC article.
Dissecting the role of PfAP2-G in malaria gametocytogenesis.
Josling GA, Russell TJ, Venezia J, Orchard L, van Biljon R, Painter HJ, Llinás M. Josling GA, et al. Nat Commun. 2020 Mar 20;11(1):1503. doi: 10.1038/s41467-020-15026-0. Nat Commun. 2020. PMID: 32198457 Free PMC article.
Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum.
Schalkwijk J, Allman EL, Jansen PAM, de Vries LE, Verhoef JMJ, Jackowski S, Botman PNM, Beuckens-Schortinghuis CA, Koolen KMJ, Bolscher JM, Vos MW, Miller K, Reeves SA, Pett H, Trevitt G, Wittlin S, Scheurer C, Sax S, Fischli C, Angulo-Barturen I, Jiménez-Diaz MB, Josling G, Kooij TWA, Bonnert R, Campo B, Blaauw RH, Rutjes FPJT, Sauerwein RW, Llinás M, Hermkens PHH, Dechering KJ. Schalkwijk J, et al. Among authors: josling g. Sci Transl Med. 2019 Sep 18;11(510):eaas9917. doi: 10.1126/scitranslmed.aas9917. Sci Transl Med. 2019. PMID: 31534021
A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression.
Josling GA, Petter M, Oehring SC, Gupta AP, Dietz O, Wilson DW, Schubert T, Längst G, Gilson PR, Crabb BS, Moes S, Jenoe P, Lim SW, Brown GV, Bozdech Z, Voss TS, Duffy MF. Josling GA, et al. Cell Host Microbe. 2015 Jun 10;17(6):741-51. doi: 10.1016/j.chom.2015.05.009. Cell Host Microbe. 2015. PMID: 26067602 Free article.
16 results