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Page 1
Glucose metabolism links astroglial mitochondria to cannabinoid effects.
Jimenez-Blasco D, Busquets-Garcia A, Hebert-Chatelain E, Serrat R, Vicente-Gutierrez C, Ioannidou C, Gómez-Sotres P, Lopez-Fabuel I, Resch-Beusher M, Resel E, Arnouil D, Saraswat D, Varilh M, Cannich A, Julio-Kalajzic F, Bonilla-Del Río I, Almeida A, Puente N, Achicallende S, Lopez-Rodriguez ML, Jollé C, Déglon N, Pellerin L, Josephine C, Bonvento G, Panatier A, Lutz B, Piazza PV, Guzmán M, Bellocchio L, Bouzier-Sore AK, Grandes P, Bolaños JP, Marsicano G. Jimenez-Blasco D, et al. Among authors: josephine c. Nature. 2020 Jul;583(7817):603-608. doi: 10.1038/s41586-020-2470-y. Epub 2020 Jul 8. Nature. 2020. PMID: 32641832
The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
Galvan L, Francelle L, Gaillard MC, de Longprez L, Carrillo-de Sauvage MA, Liot G, Cambon K, Stimmer L, Luccantoni S, Flament J, Valette J, de Chaldée M, Auregan G, Guillermier M, Joséphine C, Petit F, Jan C, Jarrige M, Dufour N, Bonvento G, Humbert S, Saudou F, Hantraye P, Merienne K, Bemelmans AP, Perrier AL, Déglon N, Brouillet E. Galvan L, et al. Among authors: josephine c. Brain. 2018 May 1;141(5):1434-1454. doi: 10.1093/brain/awy057. Brain. 2018. PMID: 29534157 Free PMC article.
Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease.
Ceyzériat K, Ben Haim L, Denizot A, Pommier D, Matos M, Guillemaud O, Palomares MA, Abjean L, Petit F, Gipchtein P, Gaillard MC, Guillermier M, Bernier S, Gaudin M, Aurégan G, Joséphine C, Déchamps N, Veran J, Langlais V, Cambon K, Bemelmans AP, Baijer J, Bonvento G, Dhenain M, Deleuze JF, Oliet SHR, Brouillet E, Hantraye P, Carrillo-de Sauvage MA, Olaso R, Panatier A, Escartin C. Ceyzériat K, et al. Among authors: josephine c. Acta Neuropathol Commun. 2018 Oct 16;6(1):104. doi: 10.1186/s40478-018-0606-1. Acta Neuropathol Commun. 2018. PMID: 30322407 Free PMC article.
Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease.
Guillemaud O, Ceyzériat K, Saint-Georges T, Cambon K, Petit F, Ben Haim L, Carrillo-de Sauvage MA, Guillermier M, Bernier S, Hérard AS, Joséphine C, Bémelmans AP, Brouillet E, Hantraye P, Bonvento G, Escartin C. Guillemaud O, et al. Among authors: josephine c. Neurobiol Aging. 2020 Jun;90:135-146. doi: 10.1016/j.neurobiolaging.2020.02.010. Epub 2020 Feb 18. Neurobiol Aging. 2020. PMID: 32171592 Free article.
Astrocytic mitochondrial ROS modulate brain metabolism and mouse behaviour.
Vicente-Gutierrez C, Bonora N, Bobo-Jimenez V, Jimenez-Blasco D, Lopez-Fabuel I, Fernandez E, Josephine C, Bonvento G, Enriquez JA, Almeida A, Bolaños JP. Vicente-Gutierrez C, et al. Among authors: josephine c. Nat Metab. 2019 Feb;1(2):201-211. doi: 10.1038/s42255-018-0031-6. Epub 2019 Feb 4. Nat Metab. 2019. PMID: 32694785
THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency.
Vautheny A, Duwat C, Aurégan G, Joséphine C, Hérard AS, Jan C, Mitja J, Gipchtein P, Gaillard MC, Buée L, Blum D, Hantraye P, Bonvento G, Brouillet E, Cambon K, Bemelmans AP. Vautheny A, et al. Among authors: josephine c. Neurobiol Dis. 2021 Jul;155:105398. doi: 10.1016/j.nbd.2021.105398. Epub 2021 May 18. Neurobiol Dis. 2021. PMID: 34019997 Free article.
Development of an AAV-based model of tauopathy targeting retinal ganglion cells and the mouse visual pathway to study the role of microglia in Tau pathology.
Duwat C, Léal P, Vautheny A, Aurégan G, Joséphine C, Gaillard MC, Hérard AS, Jan C, Gipchtein P, Mitja J, Fouquet S, Niepon ML, Hantraye P, Brouillet E, Bonvento G, Cambon K, Bemelmans AP. Duwat C, et al. Among authors: josephine c. Neurobiol Dis. 2023 Jun 1;181:106116. doi: 10.1016/j.nbd.2023.106116. Epub 2023 Apr 11. Neurobiol Dis. 2023. PMID: 37054900 Free article.
The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo.
Cresto N, Gaillard MC, Gardier C, Gubinelli F, Diguet E, Bellet D, Legroux L, Mitja J, Auregan G, Guillermier M, Josephine C, Jan C, Dufour N, Joliot A, Hantraye P, Bonvento G, Déglon N, Bemelmans AP, Cambon K, Liot G, Brouillet E. Cresto N, et al. Among authors: josephine c. Neurobiol Dis. 2020 Feb;134:104614. doi: 10.1016/j.nbd.2019.104614. Epub 2019 Oct 9. Neurobiol Dis. 2020. PMID: 31605779 Free article.
Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state.
Maté de Gérando A, d'Orange M, Augustin E, Joséphine C, Aurégan G, Gaudin-Guérif M, Guillermier M, Hérard AS, Stimmer L, Petit F, Gipchtein P, Jan C, Escartin C, Selingue E, Carvalho K, Blum D, Brouillet E, Hantraye P, Gaillard MC, Bonvento G, Bemelmans AP, Cambon K. Maté de Gérando A, et al. Among authors: josephine c. Brain. 2021 May 7;144(4):1167-1182. doi: 10.1093/brain/awab011. Brain. 2021. PMID: 33842937
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