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Transgenic, inducible RNAi in megakaryocytes and platelets in mice.
Takiguchi M, James C, Josefsson EC, Carmichael CL, Premsrirut PK, Lowe SW, Hamilton JR, Huang DC, Kile BT, Dickins RA. Takiguchi M, et al. Among authors: josefsson ec. J Thromb Haemost. 2010 Dec;8(12):2751-6. doi: 10.1111/j.1538-7836.2010.04077.x. J Thromb Haemost. 2010. PMID: 21138522 Free PMC article.
Apoptotic Ablation of Platelets Reduces Atherosclerosis in Mice With Diabetes.
Lee MKS, Kraakman MJ, Dragoljevic D, Hanssen NMJ, Flynn MC, Al-Sharea A, Sreejit G, Bertuzzo-Veiga C, Cooney OD, Baig F, Morriss E, Cooper ME, Josefsson EC, Kile BT, Nagareddy PR, Murphy AJ. Lee MKS, et al. Among authors: josefsson ec. Arterioscler Thromb Vasc Biol. 2021 Mar;41(3):1167-1178. doi: 10.1161/ATVBAHA.120.315369. Epub 2021 Jan 14. Arterioscler Thromb Vasc Biol. 2021. PMID: 33441028 Free PMC article.
Platelet intrinsic apoptosis.
Josefsson EC. Josefsson EC. Thromb Res. 2023 Nov;231:206-213. doi: 10.1016/j.thromres.2022.11.024. Epub 2022 Dec 12. Thromb Res. 2023. PMID: 36739256 Free article. Review.
N-methyl-d-aspartate receptor mediated calcium influx supports in vitro differentiation of normal mouse megakaryocytes but proliferation of leukemic cell lines.
Kamal T, Green TN, Hearn JI, Josefsson EC, Morel-Kopp MC, Ward CM, During MJ, Kalev-Zylinska ML. Kamal T, et al. Among authors: josefsson ec. Res Pract Thromb Haemost. 2017 Dec 14;2(1):125-138. doi: 10.1002/rth2.12068. eCollection 2018 Jan. Res Pract Thromb Haemost. 2017. PMID: 30046713 Free PMC article.
Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion.
Pleines I, Lebois M, Gangatirkar P, Au AE, Lane RM, Henley KJ, Kauppi M, Corbin J, Cannon P, Bernardini J, Alwis I, Jarman KE, Ellis S, Metcalf D, Jackson SP, Schoenwaelder SM, Kile BT, Josefsson EC. Pleines I, et al. Among authors: josefsson ec. Blood. 2018 Jul 12;132(2):197-209. doi: 10.1182/blood-2017-11-816355. Epub 2018 May 21. Blood. 2018. PMID: 29784641 Free article.
Platelets disrupt vasculogenic mimicry by cancer cells.
Martini C, Thompson EJ, Hyslop SR, Cockshell MP, Dale BJ, Ebert LM, Woods AE, Josefsson EC, Bonder CS. Martini C, et al. Among authors: josefsson ec. Sci Rep. 2020 Apr 3;10(1):5869. doi: 10.1038/s41598-020-62648-x. Sci Rep. 2020. PMID: 32246008 Free PMC article.
53 results