Jordan F - Search Results

1

Progress in the experimental observation of thiamin diphosphate-bound intermediates on enzymes and mechanistic information derived from these observations.

Jordan F, Nemeria NS. Jordan F, et al. Bioorg Chem. 2014 Dec;57:251-262. doi: 10.1016/j.bioorg.2014.08.002. Epub 2014 Sep 3. Bioorg Chem. 2014. PMID: 25228115 Review.

2

Effect of substitutions in the thiamin diphosphate-magnesium fold on the activation of the pyruvate dehydrogenase complex from Escherichia coli by cofactors and substrate.

Yi J, Nemeria N, McNally A, Jordan F, Machado RS, Guest JR. Yi J, et al. Among authors: jordan f. J Biol Chem. 1996 Dec 27;271(52):33192-200. doi: 10.1074/jbc.271.52.33192. J Biol Chem. 1996. PMID: 8969175 Free article.

3

2-Oxo-3-alkynoic acids, universal mechanism-based inactivators of thiamin diphosphate-dependent decarboxylases: synthesis and evidence for potent inactivation of the pyruvate dehydrogenase multienzyme complex.

Brown A, Nemeria N, Yi J, Zhang D, Jordan WB, Machado RS, Guest JR, Jordan F. Brown A, et al. Among authors: jordan wb, jordan f. Biochemistry. 1997 Jul 1;36(26):8071-81. doi: 10.1021/bi970094y. Biochemistry. 1997. PMID: 9201955

A new class of compounds, the 2-oxo-3-alkynoic acids with a phenyl substituent at carbon 4 was reported by the authors as potent irreversible and mechanism-based inhibitors of the thiamin diphosphate- (ThDP-) dependent enzyme pyruvate decarboxylase [Chiu, C.-F., & J …

A new class of compounds, the 2-oxo-3-alkynoic acids with a phenyl substituent at carbon 4 was reported by the authors as potent irreversibl …

4

Systematic study of the six cysteines of the E1 subunit of the pyruvate dehydrogenase multienzyme complex from Escherichia coli: none is essential for activity.

Nemeria N, Volkov A, Brown A, Yi J, Zipper L, Guest JR, Jordan F. Nemeria N, et al. Among authors: jordan f. Biochemistry. 1998 Jan 20;37(3):911-22. doi: 10.1021/bi9722251. Biochemistry. 1998. PMID: 9454581

5

Regulation of thiamin diphosphate-dependent 2-oxo acid decarboxylases by substrate and thiamin diphosphate.Mg(II) - evidence for tertiary and quaternary interactions.

Jordan F, Nemeria N, Guo F, Baburina I, Gao Y, Kahyaoglu A, Li H, Wang J, Yi J, Guest JR, Furey W. Jordan F, et al. Biochim Biophys Acta. 1998 Jun 29;1385(2):287-306. doi: 10.1016/s0167-4838(98)00075-2. Biochim Biophys Acta. 1998. PMID: 9655921 Review.

6

Is a hydrophobic amino acid required to maintain the reactive V conformation of thiamin at the active center of thiamin diphosphate-requiring enzymes? Experimental and computational studies of isoleucine 415 of yeast pyruvate decarboxylase.

Guo F, Zhang D, Kahyaoglu A, Farid RS, Jordan F. Guo F, et al. Among authors: jordan f. Biochemistry. 1998 Sep 22;37(38):13379-91. doi: 10.1021/bi9807097. Biochemistry. 1998. PMID: 9748345

7

Remarkable stabilization of zwitterionic intermediates may account for a billion-fold rate acceleration by thiamin diphosphate-dependent decarboxylases.

Jordan F, Li H, Brown A. Jordan F, et al. Biochemistry. 1999 May 18;38(20):6369-73. doi: 10.1021/bi990373g. Biochemistry. 1999. PMID: 10350453

8

Interplay of organic and biological chemistry in understanding coenzyme mechanisms: example of thiamin diphosphate-dependent decarboxylations of 2-oxo acids.

Jordan F. Jordan F. FEBS Lett. 1999 Sep 3;457(3):298-301. doi: 10.1016/s0014-5793(99)01061-3. FEBS Lett. 1999. PMID: 10471796 Free article. Review.

9

Spectroscopic detection of transient thiamin diphosphate-bound intermediates on benzoylformate decarboxylase.

Sergienko EA, Wang J, Polovnikova L, Hasson MS, McLeish MJ, Kenyon GL, Jordan F. Sergienko EA, et al. Among authors: jordan f. Biochemistry. 2000 Nov 14;39(45):13862-9. doi: 10.1021/bi001214w. Biochemistry. 2000. PMID: 11076527

10

Inhibition of the Escherichia coli pyruvate dehydrogenase complex E1 subunit and its tyrosine 177 variants by thiamin 2-thiazolone and thiamin 2-thiothiazolone diphosphates. Evidence for reversible tight-binding inhibition.

Nemeria N, Yan Y, Zhang Z, Brown AM, Arjunan P, Furey W, Guest JR, Jordan F. Nemeria N, et al. Among authors: jordan f. J Biol Chem. 2001 Dec 7;276(49):45969-78. doi: 10.1074/jbc.M104116200. Epub 2001 Oct 2. J Biol Chem. 2001. PMID: 11583990 Free article.

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